Regional cerebral blood flow patterns during verbal and nonverbal auditory activation

David S Knopman, Alan B. Rubens, Arthur C. Klassen, Maurice W. Meyer, Nancy Niccum

Research output: Contribution to journalArticle

29 Citations (Scopus)

Abstract

Current views of the relationship between audition and cerebral function suggest that increases in regional cerebral blood flow (rCBF) would occur in the superior, mid, and posterior portions of the temporal lobes, and that these changes would be more lateralized to the left hemisphere for a verbal than a nonverbal auditory task. We measured rCBF using the xenon inhalation technique in a group of healthy subjects during three conditions: (1) resting baseline, (2) auditory verbal activation (listening for word meaning), and (3) auditory nonverbal activation (listening for reduction of intensity in a series of noise bursts). Both verbal and nonverbal conditions produced highly significant increases in rCBF over the left posterior Sylvian region with a trend for verbal activation to evoke a wider area of flow increase than the nonverbal task.

Original languageEnglish (US)
Pages (from-to)93-112
Number of pages20
JournalBrain and Language
Volume9
Issue number1
DOIs
StatePublished - 1980
Externally publishedYes

Fingerprint

Cerebrovascular Circulation
Regional Blood Flow
activation
Xenon
Temporal Lobe
Inhalation
Hearing
Noise
Healthy Volunteers
trend
Activation
Regional Cerebral Blood Flow
Group

ASJC Scopus subject areas

  • Language and Linguistics
  • Neuroscience(all)
  • Experimental and Cognitive Psychology
  • Neuropsychology and Physiological Psychology

Cite this

Regional cerebral blood flow patterns during verbal and nonverbal auditory activation. / Knopman, David S; Rubens, Alan B.; Klassen, Arthur C.; Meyer, Maurice W.; Niccum, Nancy.

In: Brain and Language, Vol. 9, No. 1, 1980, p. 93-112.

Research output: Contribution to journalArticle

Knopman, David S ; Rubens, Alan B. ; Klassen, Arthur C. ; Meyer, Maurice W. ; Niccum, Nancy. / Regional cerebral blood flow patterns during verbal and nonverbal auditory activation. In: Brain and Language. 1980 ; Vol. 9, No. 1. pp. 93-112.
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