Reducing the load: The evolution and management of obesity and nonalcoholic steatohepatitis before liver transplantation

Kymberly D. Watt

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

Key Points 1. Obesity is common in patients with end-stage liver disease of any cause. 2. Obesity is associated with comorbidities that can affect liver transplant candidacy, such as metabolic syndrome (diabetes, hyperlipidemia, and hypertension), cardiovascular disease, pulmonary disorders (related to obstructive sleep apnea), renal dysfunction, and malignancies. 3. Nonalcoholic steatohepatitis is the only indication for transplantation that is increasing in frequency, and it may soon become the leading indication. 4. There is no set body mass index above which liver transplantation is contraindicated. Transplant candidacy and outcomes depend on the cumulative comorbidities of the individual patient. 5. Weight loss is an important component of metabolic syndrome management and is recommended before liver transplantation. 6. Bariatric surgery may be considered in carefully selected patients with well-compensated cirrhosis but is not recommended in patients with decompensated cirrhosis.

Original languageEnglish (US)
JournalLiver Transplantation
Volume18
Issue numberSUPPL.2
DOIs
StatePublished - Nov 2012

Fingerprint

Liver Transplantation
Obesity
Comorbidity
Fibrosis
Transplants
End Stage Liver Disease
Bariatric Surgery
Obstructive Sleep Apnea
Hyperlipidemias
Weight Loss
Body Mass Index
Cardiovascular Diseases
Transplantation
Hypertension
Kidney
Lung
Non-alcoholic Fatty Liver Disease
Liver
Neoplasms

ASJC Scopus subject areas

  • Surgery
  • Transplantation
  • Hepatology

Cite this

Reducing the load : The evolution and management of obesity and nonalcoholic steatohepatitis before liver transplantation. / Watt, Kymberly D.

In: Liver Transplantation, Vol. 18, No. SUPPL.2, 11.2012.

Research output: Contribution to journalArticle

@article{6477ed5204e446b7947415cc33f94ead,
title = "Reducing the load: The evolution and management of obesity and nonalcoholic steatohepatitis before liver transplantation",
abstract = "Key Points 1. Obesity is common in patients with end-stage liver disease of any cause. 2. Obesity is associated with comorbidities that can affect liver transplant candidacy, such as metabolic syndrome (diabetes, hyperlipidemia, and hypertension), cardiovascular disease, pulmonary disorders (related to obstructive sleep apnea), renal dysfunction, and malignancies. 3. Nonalcoholic steatohepatitis is the only indication for transplantation that is increasing in frequency, and it may soon become the leading indication. 4. There is no set body mass index above which liver transplantation is contraindicated. Transplant candidacy and outcomes depend on the cumulative comorbidities of the individual patient. 5. Weight loss is an important component of metabolic syndrome management and is recommended before liver transplantation. 6. Bariatric surgery may be considered in carefully selected patients with well-compensated cirrhosis but is not recommended in patients with decompensated cirrhosis.",
author = "Watt, {Kymberly D.}",
year = "2012",
month = "11",
doi = "10.1002/lt.23515",
language = "English (US)",
volume = "18",
journal = "Liver Transplantation",
issn = "1527-6465",
publisher = "John Wiley and Sons Ltd",
number = "SUPPL.2",

}

TY - JOUR

T1 - Reducing the load

T2 - The evolution and management of obesity and nonalcoholic steatohepatitis before liver transplantation

AU - Watt, Kymberly D.

PY - 2012/11

Y1 - 2012/11

N2 - Key Points 1. Obesity is common in patients with end-stage liver disease of any cause. 2. Obesity is associated with comorbidities that can affect liver transplant candidacy, such as metabolic syndrome (diabetes, hyperlipidemia, and hypertension), cardiovascular disease, pulmonary disorders (related to obstructive sleep apnea), renal dysfunction, and malignancies. 3. Nonalcoholic steatohepatitis is the only indication for transplantation that is increasing in frequency, and it may soon become the leading indication. 4. There is no set body mass index above which liver transplantation is contraindicated. Transplant candidacy and outcomes depend on the cumulative comorbidities of the individual patient. 5. Weight loss is an important component of metabolic syndrome management and is recommended before liver transplantation. 6. Bariatric surgery may be considered in carefully selected patients with well-compensated cirrhosis but is not recommended in patients with decompensated cirrhosis.

AB - Key Points 1. Obesity is common in patients with end-stage liver disease of any cause. 2. Obesity is associated with comorbidities that can affect liver transplant candidacy, such as metabolic syndrome (diabetes, hyperlipidemia, and hypertension), cardiovascular disease, pulmonary disorders (related to obstructive sleep apnea), renal dysfunction, and malignancies. 3. Nonalcoholic steatohepatitis is the only indication for transplantation that is increasing in frequency, and it may soon become the leading indication. 4. There is no set body mass index above which liver transplantation is contraindicated. Transplant candidacy and outcomes depend on the cumulative comorbidities of the individual patient. 5. Weight loss is an important component of metabolic syndrome management and is recommended before liver transplantation. 6. Bariatric surgery may be considered in carefully selected patients with well-compensated cirrhosis but is not recommended in patients with decompensated cirrhosis.

UR - http://www.scopus.com/inward/record.url?scp=84868117362&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84868117362&partnerID=8YFLogxK

U2 - 10.1002/lt.23515

DO - 10.1002/lt.23515

M3 - Article

C2 - 22821716

AN - SCOPUS:84868117362

VL - 18

JO - Liver Transplantation

JF - Liver Transplantation

SN - 1527-6465

IS - SUPPL.2

ER -