TY - JOUR
T1 - Recurrent spontaneous coronary artery dissection in the United States
AU - Krittanawong, Chayakrit
AU - Kumar, Anirudh
AU - Virk, Hafeez Ul Hassan
AU - Wang, Zhen
AU - Johnson, Kipp W.
AU - Yue, Bing
AU - Bhatt, Deepak L.
N1 - Publisher Copyright:
© 2019 Elsevier B.V.
PY - 2020/2/15
Y1 - 2020/2/15
N2 - Background: Recurrent spontaneous coronary artery dissection (SCAD) is believed to be infrequent. Predictors of recurrent SCAD are poorly characterized. Methods: We evaluated the incidence, clinical characteristics, and predictors of recurrent SCAD using data from the Nationwide Readmissions Database from January 1, 2010, to December 30, 2016. Results: Among 1836 SCAD patients admitted with the primary diagnosis of SCAD (61.9% female, mean age 56.1 ± 14.5, 72.9% <65 years of age), 495 patients (26.9%) had recurrent SCAD within 1 year (74.0% female, 74% <65 years of age). Multivariable analysis showed that female sex (OR 2.09; 95% CI 1.49–2.95; p < 0.001) was an independent predictor of recurrent SCAD within 1 year. Conclusions: Recurrent SCAD is frequent and should be considered in younger females with a history of SCAD. Further research is needed to investigate the mechanistic links between female sex and recurrent SCAD.
AB - Background: Recurrent spontaneous coronary artery dissection (SCAD) is believed to be infrequent. Predictors of recurrent SCAD are poorly characterized. Methods: We evaluated the incidence, clinical characteristics, and predictors of recurrent SCAD using data from the Nationwide Readmissions Database from January 1, 2010, to December 30, 2016. Results: Among 1836 SCAD patients admitted with the primary diagnosis of SCAD (61.9% female, mean age 56.1 ± 14.5, 72.9% <65 years of age), 495 patients (26.9%) had recurrent SCAD within 1 year (74.0% female, 74% <65 years of age). Multivariable analysis showed that female sex (OR 2.09; 95% CI 1.49–2.95; p < 0.001) was an independent predictor of recurrent SCAD within 1 year. Conclusions: Recurrent SCAD is frequent and should be considered in younger females with a history of SCAD. Further research is needed to investigate the mechanistic links between female sex and recurrent SCAD.
KW - Recurrent spontaneous coronary artery dissection
KW - SCAD
KW - Spontaneous coronary artery dissection
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U2 - 10.1016/j.ijcard.2019.10.052
DO - 10.1016/j.ijcard.2019.10.052
M3 - Article
C2 - 31757645
AN - SCOPUS:85076202449
SN - 0167-5273
VL - 301
SP - 34
EP - 37
JO - International Journal of Cardiology
JF - International Journal of Cardiology
ER -