Recurrent glioblastoma multiforme is a lethal disease with currently available treatment options having a limited impact on outcome. In this article, current and novel therapeutic approaches in the treatment of recurrent glioblastoma multiforme, including chemotherapy, targeted molecular agents, virotherapy/gene therapy and immunotherapy and challenges in developing novel therapeutic agents for glioblastoma multiforme will be discussed.
- Gene therapy
- Glioblastoma multiforme
- Small molecule cell cycle inhibitors
ASJC Scopus subject areas
- Pharmacology (medical)