@article{31b703b28b4b4f0faf0f318c5377b388,
title = "Recreational physical inactivity and mortality in women with invasive epithelial ovarian cancer: Evidence from the Ovarian Cancer Association Consortium",
abstract = "Background: Little is known about modifiable behaviours that may be associated with epithelial ovarian cancer (EOC) survival. We conducted a pooled analysis of 12 studies from the Ovarian Cancer Association Consortium to investigate the association between pre-diagnostic physical inactivity and mortality. Methods: Participants included 6806 women with a primary diagnosis of invasive EOC. In accordance with the Physical Activity Guidelines for Americans, women reporting no regular, weekly recreational physical activity were classified as inactive. We utilised Cox proportional hazard models to estimate hazard ratios (HRs) and 95% confidence intervals (CIs) representing the associations of inactivity with mortality censored at 5 years. Results: In multivariate analysis, inactive women had significantly higher mortality risks, with (HR=1.34, 95% CI: 1.18-1.52) and without (HR=1.22, 95% CI: 1.12-1.33) further adjustment for residual disease, respectively. Conclusion: In this large pooled analysis, lack of recreational physical activity was associated with increased mortality among women with invasive EOC.",
keywords = "epithelial ovarian cancer, inactivity, mortality risk, recreational physical activity, survival",
author = "Cannioto, {Rikki A.} and LaMonte, {Michael J.} and Kelemen, {Linda E.} and Risch, {Harvey A.} and Eng, {Kevin H.} and Minlikeeva, {Albina N.} and Hong, {Chi Chen} and Szender, {J. Brian} and Lara Sucheston-Campbell and Joseph, {Janine M.} and Andrew Berchuck and Jenny Chang-Claude and Cramer, {Daniel W.} and {De Fazio}, Anna and Brenda Diergaarde and Thilo D{\"o}rk and Doherty, {Jennifer A.} and Edwards, {Robert P.} and Fridley, {Brooke L.} and Grace Friel and Goode, {Ellen L.} and Goodman, {Marc T.} and Peter Hillemanns and Estrid Hogdall and Satoyo Hosono and Kelley, {Joseph L.} and Kjaer, {Susanne K.} and Rudiger Klapdor and Keitaro Matsuo and Kunle Odunsi and Nagle, {Christina M.} and Olsen, {Catherine M.} and Paddock, {Lisa E.} and Pearce, {Celeste L.} and Pike, {Malcolm C.} and Rossing, {Mary A.} and Barbara Schmalfeldt and Segal, {Brahm H.} and Szamreta, {Elizabeth A.} and Thompson, {Pamela J.} and Tseng, {Chiu Chen} and Robert Vierkant and Schildkraut, {Joellen M.} and Nicolas Wentzensen and Wicklund, {Kristine G.} and Winham, {Stacey J.} and Wu, {Anna H.} and Francesmary Modugno and Ness, {Roberta B.} and Allan Jensen and Webb, {Penelope M.} and Kathryn Terry and Bandera, {Elisa V.} and Moysich, {Kirsten B.}",
note = "Publisher Copyright: {\textcopyright} 2016 Cancer Research UK.",
year = "2016",
month = jun,
day = "28",
doi = "10.1038/bjc.2016.153",
language = "English (US)",
volume = "115",
pages = "95--101",
journal = "British journal of cancer",
issn = "0007-0920",
publisher = "Nature Publishing Group",
number = "1",
}