Reconstruction of extensive defects from posterior en bloc resection of sacral tumors with human acellular dermal matrix and gluteus maximus myocutaneous flaps

Hormuzdiyar H. Dasenbrock, Michelle J. Clarke, Ali Bydon, Timothy F. Witham, Daniel M. Sciubba, Oliver P. Simmons, Ziya L. Gokaslan, Jean Paul Wolinsky

Research output: Contribution to journalArticlepeer-review

22 Scopus citations

Abstract

BACKGROUND: Performing a sacrectomy from an exclusively posterior approach allows the en bloc resection of tumors without the morbidity of a laparotomy. However, reconstruction of the resultant extensive soft-tissue defects is challenging because a vertical rectus abdominis myocutaneous flap is not harvested. OBJECTIVE: To report the largest series (with the longest follow-up) of sacral reconstructions using a combination of human acellular dermal matrix (HADM) and gluteus maximus myocutaneous flaps. METHODS: Thirty-four patients with sacral tumors with a follow-up of at least 1 year were reviewed retrospectively. After the tumor was excised, HADM (AlloDerm, LifeCell Corp, Branchburg, New Jersey) was secured to create a pelvic diaphragm. Subsequently, the gluteus maximus muscles were freed from their origins and advanced to cover the HADM. RESULTS: The mean age of patients was 50.1 years (SD, 16.0 years), and the histopathology was a chordoma in 82.4%. Seven patients (20.6%) developed a postoperative wound dehiscence, 5 of whom (14.7%) required operative debridement. An estimated blood loss of >1500 mL, an operative time of >9 hours during sacrectomy, and postoperative bowel incontinence were associated with a significantly higher likelihood of undergoing a subsequent debridement for dehiscence (P ≤ .03). With a mean follow-up of 45.7 months, only 1 patient developed an asymptomatic parasacral hernia. CONCLUSION: Reconstruction of posterior sacrectomy defects with HADM and gluteus maximus myocutaneous flaps may be valid. This approach may have rates of wound dehiscence comparable to other techniques and low rates of parasacral herniation.

Original languageEnglish (US)
Pages (from-to)1240-1247
Number of pages8
JournalNeurosurgery
Volume69
Issue number6
DOIs
StatePublished - Dec 2011

Keywords

  • Chordoma
  • Gluteus maximus myocutaneous flap
  • Human acellular dermal matrix
  • Sacral hernia
  • Sacral reconstruction
  • Sacral tumors
  • Sacrectomy

ASJC Scopus subject areas

  • Surgery
  • Clinical Neurology

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