Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the Diagnosis of Multiple Sclerosis

W. Ian McDonald; Alistair Compston; Gilles Edan; Donald Goodkin; Hans Peter Hartung; Fred D. Lublin; Henry F. McFarland; Donald W. Paty; Chris H. Polman; Stephen C. Reingold; Magnhild Sandberg-Wollheim; William Sibley; Alan Thompson; Stanley Van Den Noort; Brian Y. Weinshenker; Jerry S. Wolinsky

doi:10.1002/ana.1032

Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the Diagnosis of Multiple Sclerosis

W. Ian McDonald, Alistair Compston, Gilles Edan, Donald Goodkin, Hans Peter Hartung, Fred D. Lublin, Henry F. McFarland, Donald W. Paty, Chris H. Polman, Stephen C. Reingold, Magnhild Sandberg-Wollheim, William Sibley, Alan Thompson, Stanley Van Den Noort, Brian Y. Weinshenker, Jerry S. Wolinsky

Neurology

Research output: Contribution to journal › Article › peer-review

5603 Scopus citations

Abstract

The International Panel on MS Diagnosis presents revised diagnostic criteria for multiple sclerosis (MS). The focus remains on the objective demonstration of dissemination of lesions in both time and space. Magnetic resonance imaging is integrated with clinical and other paraclinical diagnostic methods. The revised criteria facilitate the diagnosis of MS in patients with a variety of presentations, including "monosymptomatic" disease suggestive of MS, disease with a typical relapsing-remitting course, and disease with insidious progression, without dear attacks and remissions. Previously used terms such as "clinically definite" and "probable MS" are no longer recommended. The outcome of a diagnostic evaluation is either MS, "possible MS" (for those at risk for MS, but for whom diagnostic evaluation is equivocal), or "not MS".

Original language	English (US)
Pages (from-to)	121-127
Number of pages	7
Journal	Annals of neurology
Volume	50
Issue number	1
DOIs	https://doi.org/10.1002/ana.1032
State	Published - 2001

ASJC Scopus subject areas

Neurology
Clinical Neurology

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McDonald, W. I., Compston, A., Edan, G., Goodkin, D., Hartung, H. P., Lublin, F. D., McFarland, H. F., Paty, D. W., Polman, C. H., Reingold, S. C., Sandberg-Wollheim, M., Sibley, W., Thompson, A., Van Den Noort, S., Weinshenker, B. Y., & Wolinsky, J. S. (2001). Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the Diagnosis of Multiple Sclerosis. Annals of neurology, 50(1), 121-127. https://doi.org/10.1002/ana.1032

McDonald, WI, Compston, A, Edan, G, Goodkin, D, Hartung, HP, Lublin, FD, McFarland, HF, Paty, DW, Polman, CH, Reingold, SC, Sandberg-Wollheim, M, Sibley, W, Thompson, A, Van Den Noort, S, Weinshenker, BY & Wolinsky, JS 2001, 'Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the Diagnosis of Multiple Sclerosis', Annals of neurology, vol. 50, no. 1, pp. 121-127. https://doi.org/10.1002/ana.1032

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title = "Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the Diagnosis of Multiple Sclerosis",

abstract = "The International Panel on MS Diagnosis presents revised diagnostic criteria for multiple sclerosis (MS). The focus remains on the objective demonstration of dissemination of lesions in both time and space. Magnetic resonance imaging is integrated with clinical and other paraclinical diagnostic methods. The revised criteria facilitate the diagnosis of MS in patients with a variety of presentations, including {"}monosymptomatic{"} disease suggestive of MS, disease with a typical relapsing-remitting course, and disease with insidious progression, without dear attacks and remissions. Previously used terms such as {"}clinically definite{"} and {"}probable MS{"} are no longer recommended. The outcome of a diagnostic evaluation is either MS, {"}possible MS{"} (for those at risk for MS, but for whom diagnostic evaluation is equivocal), or {"}not MS{"}.",

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AU - Goodkin, Donald

AU - Hartung, Hans Peter

AU - Lublin, Fred D.

AU - McFarland, Henry F.

AU - Paty, Donald W.

AU - Polman, Chris H.

AU - Reingold, Stephen C.

AU - Sandberg-Wollheim, Magnhild

AU - Sibley, William

AU - Thompson, Alan

AU - Van Den Noort, Stanley

AU - Weinshenker, Brian Y.

AU - Wolinsky, Jerry S.

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Recommended diagnostic criteria for multiple sclerosis: Guidelines from the International Panel on the Diagnosis of Multiple Sclerosis

Abstract

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