Recognition of genetic syndromes in families with suspected hereditary colon cancer syndromes

Research output: Contribution to journalReview article

16 Scopus citations


There is an increasing number of genetic disorders that predispose to colorectal cancer. Although these syndromes probably account for <5% of colorectal cancers, clinical recognition of these disorders is essential to assure the best clinical recommendations. There are increased risks for second cancers - both GI and non-GI cancers - in the patients and their relatives. Diagnosis of a familial cancer predisposition syndrome guides clinical management including early detection and prevention of cancers in such families.

Original languageEnglish (US)
Pages (from-to)366-375
Number of pages10
JournalClinical Gastroenterology and Hepatology
Issue number5
StatePublished - May 2004



  • GI
  • IHC
  • MSI
  • gastrointestinal
  • hereditary nonpolyposis colon cancer
  • immunohistochemistry
  • microsatellite instability

ASJC Scopus subject areas

  • Hepatology
  • Gastroenterology

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