Real-World Incidence of Breakthrough Coronavirus Disease 2019 Hospitalization After Vaccination vs Natural Infection in a Large, Local, Empaneled Primary Care Population Using Time-to-Event Analysis

Benjamin D. Pollock, Curtis B. Storlie, Aaron J. Tande, Priya Sampathkumar

Research output: Contribution to journalArticlepeer-review

Abstract

We followed 106 349 primary care patients for 22 385 3099 person-days across 21 calendar months and documented 69 breakthrough coronavirus disease 2019 (COVID-19) hospitalizations: 65/102,613 (0.06%) among those fully vaccinated, 3/11 047 (0.03%) among those previously infected, and 1/7,313 (0.01%) among those with both statuses. These data give providers real-world context regarding breakthrough COVID-19 hospitalization risk.

Original languageEnglish (US)
Pages (from-to)1239-1241
Number of pages3
JournalClinical infectious diseases : an official publication of the Infectious Diseases Society of America
Volume75
Issue number7
DOIs
StatePublished - Sep 30 2022

Keywords

  • COVID-19
  • breakthrough
  • natural immunity
  • vaccination

ASJC Scopus subject areas

  • Microbiology (medical)
  • Infectious Diseases

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