Real-time strain rate echocardiographic imaging: Temporal and spatial analysis of postsystolic compression in acutely ischemic myocardium

Marek Belohlavek; Cristina Pislaru; Richard Y. Bae; James F. Greenleaf; James B. Seward

doi:10.1067/mje.2001.110786

Real-time strain rate echocardiographic imaging: Temporal and spatial analysis of postsystolic compression in acutely ischemic myocardium

Marek Belohlavek, Cristina Pislaru, Richard Y. Bae, James F. Greenleaf, James B. Seward

Research output: Contribution to journal › Article › peer-review

40 Scopus citations

Abstract

Postsystolic compression (PSC) is a sensitive indicator of regional left ventricular ischemic diastolic dysfunction. Quantitative assessment of compression patterns by strain rate imaging could determine the presence and spatial extent of PSC for the detection and analysis of acute ischemic diastolic dysfunction. With the use of a segmental left ventricular model, we evaluated time to compression/expansion crossover (T-CEC) in standard apical views. Data at baseline and after acute left anterior descending coronary artery occlusion were collected from 18 open-chest pigs. We found significant mean prolongation of T-CEC, ranging from 43.9 ± 48.6 ms to 110.8 ± 73.8 ms, in all apical segments and in 2 midventricular (anterior and anteroseptal) segments. Analysis of variance demonstrated that the prolonged T-CEC is spatially consistent with perfusion defect. The temporal and spatial analysis of T-CEC with the use of strain rate imaging is a new noninvasive technique for identification and topographic quantitation of ischemic diastolic dysfunction expressed by PSC.

Original language	English (US)
Pages (from-to)	360-369
Number of pages	10
Journal	Journal of the American Society of Echocardiography
Volume	14
Issue number	5
DOIs	https://doi.org/10.1067/mje.2001.110786
State	Published - 2001

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging
Cardiology and Cardiovascular Medicine

Access to Document

10.1067/mje.2001.110786

Cite this

@article{74ca7051737a4a6f85c26317fd75ab83,

title = "Real-time strain rate echocardiographic imaging: Temporal and spatial analysis of postsystolic compression in acutely ischemic myocardium",

abstract = "Postsystolic compression (PSC) is a sensitive indicator of regional left ventricular ischemic diastolic dysfunction. Quantitative assessment of compression patterns by strain rate imaging could determine the presence and spatial extent of PSC for the detection and analysis of acute ischemic diastolic dysfunction. With the use of a segmental left ventricular model, we evaluated time to compression/expansion crossover (T-CEC) in standard apical views. Data at baseline and after acute left anterior descending coronary artery occlusion were collected from 18 open-chest pigs. We found significant mean prolongation of T-CEC, ranging from 43.9 ± 48.6 ms to 110.8 ± 73.8 ms, in all apical segments and in 2 midventricular (anterior and anteroseptal) segments. Analysis of variance demonstrated that the prolonged T-CEC is spatially consistent with perfusion defect. The temporal and spatial analysis of T-CEC with the use of strain rate imaging is a new noninvasive technique for identification and topographic quantitation of ischemic diastolic dysfunction expressed by PSC.",

author = "Marek Belohlavek and Cristina Pislaru and Bae, {Richard Y.} and Greenleaf, {James F.} and Seward, {James B.}",

note = "Funding Information: We thank Dr Sorin Pislaru (University of Leuven, Belgium) for assisting with statistical analysis, Julie M. Patterson for preparation of illustrations, and Jamie R. Schmeling for handling the manuscript. This work was supported in part by a Clinical Research Grant from the Mayo Clinic and Foundation. The ultrasonographic scanner and experimental software were provided courtesy of GE Medical Systems, Milwaukee, Wis. The contrast medium was provided courtesy of Nycomed Imaging AS, Oslo, Norway.",

year = "2001",

doi = "10.1067/mje.2001.110786",

language = "English (US)",

volume = "14",

pages = "360--369",

journal = "Journal of the American Society of Echocardiography",

issn = "0894-7317",

publisher = "Mosby Inc.",

number = "5",

}

TY - JOUR

T1 - Real-time strain rate echocardiographic imaging

T2 - Temporal and spatial analysis of postsystolic compression in acutely ischemic myocardium

AU - Belohlavek, Marek

AU - Pislaru, Cristina

AU - Bae, Richard Y.

AU - Greenleaf, James F.

AU - Seward, James B.

N1 - Funding Information: We thank Dr Sorin Pislaru (University of Leuven, Belgium) for assisting with statistical analysis, Julie M. Patterson for preparation of illustrations, and Jamie R. Schmeling for handling the manuscript. This work was supported in part by a Clinical Research Grant from the Mayo Clinic and Foundation. The ultrasonographic scanner and experimental software were provided courtesy of GE Medical Systems, Milwaukee, Wis. The contrast medium was provided courtesy of Nycomed Imaging AS, Oslo, Norway.

PY - 2001

Y1 - 2001

N2 - Postsystolic compression (PSC) is a sensitive indicator of regional left ventricular ischemic diastolic dysfunction. Quantitative assessment of compression patterns by strain rate imaging could determine the presence and spatial extent of PSC for the detection and analysis of acute ischemic diastolic dysfunction. With the use of a segmental left ventricular model, we evaluated time to compression/expansion crossover (T-CEC) in standard apical views. Data at baseline and after acute left anterior descending coronary artery occlusion were collected from 18 open-chest pigs. We found significant mean prolongation of T-CEC, ranging from 43.9 ± 48.6 ms to 110.8 ± 73.8 ms, in all apical segments and in 2 midventricular (anterior and anteroseptal) segments. Analysis of variance demonstrated that the prolonged T-CEC is spatially consistent with perfusion defect. The temporal and spatial analysis of T-CEC with the use of strain rate imaging is a new noninvasive technique for identification and topographic quantitation of ischemic diastolic dysfunction expressed by PSC.

AB - Postsystolic compression (PSC) is a sensitive indicator of regional left ventricular ischemic diastolic dysfunction. Quantitative assessment of compression patterns by strain rate imaging could determine the presence and spatial extent of PSC for the detection and analysis of acute ischemic diastolic dysfunction. With the use of a segmental left ventricular model, we evaluated time to compression/expansion crossover (T-CEC) in standard apical views. Data at baseline and after acute left anterior descending coronary artery occlusion were collected from 18 open-chest pigs. We found significant mean prolongation of T-CEC, ranging from 43.9 ± 48.6 ms to 110.8 ± 73.8 ms, in all apical segments and in 2 midventricular (anterior and anteroseptal) segments. Analysis of variance demonstrated that the prolonged T-CEC is spatially consistent with perfusion defect. The temporal and spatial analysis of T-CEC with the use of strain rate imaging is a new noninvasive technique for identification and topographic quantitation of ischemic diastolic dysfunction expressed by PSC.

UR - http://www.scopus.com/inward/record.url?scp=0035176272&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0035176272&partnerID=8YFLogxK

U2 - 10.1067/mje.2001.110786

DO - 10.1067/mje.2001.110786

M3 - Article

C2 - 11337681

AN - SCOPUS:0035176272

SN - 0894-7317

VL - 14

SP - 360

EP - 369

JO - Journal of the American Society of Echocardiography

JF - Journal of the American Society of Echocardiography

IS - 5

ER -

Real-time strain rate echocardiographic imaging: Temporal and spatial analysis of postsystolic compression in acutely ischemic myocardium

Abstract

ASJC Scopus subject areas

Access to Document

Other files and links

Fingerprint

Cite this