TY - JOUR
T1 - Reader Performance as a Function of Patient Size for the Detection of Hepatic Metastases
AU - Gong, Hao
AU - Yu, Lifeng
AU - Leng, Shuai
AU - Fletcher, Joel G.
AU - McCollough, Cynthia H.
N1 - Publisher Copyright:
Copyright © 2021 Wolters Kluwer Health, Inc. All rights reserved.
PY - 2021/11/1
Y1 - 2021/11/1
N2 - OBJECTIVE: To investigate reader performance as a function of patient size for the detection of hepatic metastases when an automatic exposure control (AEC) system is used, which varies image noise as a function of patient size. METHODS: Abdominal computed tomograhy examinations across 100, 120, 160, and 200 quality reference tube current-time product were collected, involving a cohort of 83 patients. Three radiologists identified hepatic metastases across all dose levels. Partial Spearman rank correlation and multivariate logistic regression were used to evaluate correlations between reader performance and patient size and lesion size/contrast while accounting for potential confounding effects. Analyses were repeated on an emulated less-variable noise AEC. RESULTS: No statistically significant correlation was observed between patient size and radiologist performance (for variable-noise AEC: range of partial Spearman ρ, -0.157 to -0.035]; range of adjusted odds ratios, 0.987, 1.006). CONCLUSIONS: Reader performance was independent of patient size, suggesting that variable-noise AEC provides better modulation for larger patients than constant-noise AEC.
AB - OBJECTIVE: To investigate reader performance as a function of patient size for the detection of hepatic metastases when an automatic exposure control (AEC) system is used, which varies image noise as a function of patient size. METHODS: Abdominal computed tomograhy examinations across 100, 120, 160, and 200 quality reference tube current-time product were collected, involving a cohort of 83 patients. Three radiologists identified hepatic metastases across all dose levels. Partial Spearman rank correlation and multivariate logistic regression were used to evaluate correlations between reader performance and patient size and lesion size/contrast while accounting for potential confounding effects. Analyses were repeated on an emulated less-variable noise AEC. RESULTS: No statistically significant correlation was observed between patient size and radiologist performance (for variable-noise AEC: range of partial Spearman ρ, -0.157 to -0.035]; range of adjusted odds ratios, 0.987, 1.006). CONCLUSIONS: Reader performance was independent of patient size, suggesting that variable-noise AEC provides better modulation for larger patients than constant-noise AEC.
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U2 - 10.1097/RCT.0000000000001200
DO - 10.1097/RCT.0000000000001200
M3 - Article
C2 - 34347711
AN - SCOPUS:85121963712
VL - 45
SP - 812
EP - 819
JO - Journal of Computer Assisted Tomography
JF - Journal of Computer Assisted Tomography
SN - 0363-8715
IS - 6
ER -