Abstract
Mitochondria-generated reactive oxygen species have been implicated as a common feature that connects aging of organisms and age-related diseases. Efficient elimination of these radicals by antioxidants correlates with increased life span. Understanding how the mitochondrion signals to the nucleus to regulate antioxidant proteins might be a key to aging processes and treatment of human diseases.
Original language | English (US) |
---|---|
Pages (from-to) | re3 |
Journal | Science's STKE : signal transduction knowledge environment |
Volume | 2006 |
Issue number | 332 |
DOIs | |
State | Published - Apr 25 2006 |
ASJC Scopus subject areas
- Medicine(all)