Rates of colon and rectal cancers are increasing in young adults

Jessica B. O'Connell, Melinda A. Maggard, Jerome H. Liu, David A. Etzioni, Edward H. Livingston, Clifford Ko

Research output: Contribution to journalArticle

201 Citations (Scopus)

Abstract

Incidence rates for colorectal cancer are decreasing in the United States, possibly due to preventative cancer screening. Because these programs target older patients, their beneficial effects may not apply to young patients. The purpose of this study was to compare incidence rates and tumor characteristics of colon and rectal cancers for young versus older patients using a population-based cancer registry. Colon and rectal cancer patients reported in the Surveillance, Epidemiology, and End Results registry (1973-1999) were separately analyzed. Incidence rates over time, stage, and grade were compared for two age groups: young patients (20-40 years, n = 5383) and older patients (60+ years, n = 256,401). For older patients, colon cancer incidence remained stable while rectal cancer incidence decreased 11 per cent to 72.1/100,000 persons (P < 0.05). For the young, colon cancer incidence increased 17 per cent to 2.1 (P < 0.05), and rectal incidence rose 75 per cent to 1.4 (P < 0.05). Young patients had less localized tumors than older patients: colon (25.8% vs. 35.3%, P < 0.001); rectal (38.4% vs. 41.7%, P = 0.005). Young patients also had more poorly differentiated tumors: colon (22.2% vs. 14.7%, P < 0.001); rectal (16.4% vs. 12.3%, P < 0.001). Incidence rates for colon and rectal cancers in young patients are rising, and they have more advanced disease. Although the overall prevalence is low in this population, the increasing incidence suggests health-care providers should have heightened awareness when caring for this population.

Original languageEnglish (US)
Pages (from-to)866-872
Number of pages7
JournalAmerican Surgeon
Volume69
Issue number10
StatePublished - 2003
Externally publishedYes

Fingerprint

Rectal Neoplasms
Colonic Neoplasms
Young Adult
Incidence
Registries
Neoplasms
Colon
Population
Early Detection of Cancer
Health Personnel
Colorectal Neoplasms
Epidemiology
Age Groups

ASJC Scopus subject areas

  • Surgery

Cite this

O'Connell, J. B., Maggard, M. A., Liu, J. H., Etzioni, D. A., Livingston, E. H., & Ko, C. (2003). Rates of colon and rectal cancers are increasing in young adults. American Surgeon, 69(10), 866-872.

Rates of colon and rectal cancers are increasing in young adults. / O'Connell, Jessica B.; Maggard, Melinda A.; Liu, Jerome H.; Etzioni, David A.; Livingston, Edward H.; Ko, Clifford.

In: American Surgeon, Vol. 69, No. 10, 2003, p. 866-872.

Research output: Contribution to journalArticle

O'Connell, JB, Maggard, MA, Liu, JH, Etzioni, DA, Livingston, EH & Ko, C 2003, 'Rates of colon and rectal cancers are increasing in young adults', American Surgeon, vol. 69, no. 10, pp. 866-872.
O'Connell JB, Maggard MA, Liu JH, Etzioni DA, Livingston EH, Ko C. Rates of colon and rectal cancers are increasing in young adults. American Surgeon. 2003;69(10):866-872.
O'Connell, Jessica B. ; Maggard, Melinda A. ; Liu, Jerome H. ; Etzioni, David A. ; Livingston, Edward H. ; Ko, Clifford. / Rates of colon and rectal cancers are increasing in young adults. In: American Surgeon. 2003 ; Vol. 69, No. 10. pp. 866-872.
@article{f4b3042d5ef24e0b9f7c9ec33886102e,
title = "Rates of colon and rectal cancers are increasing in young adults",
abstract = "Incidence rates for colorectal cancer are decreasing in the United States, possibly due to preventative cancer screening. Because these programs target older patients, their beneficial effects may not apply to young patients. The purpose of this study was to compare incidence rates and tumor characteristics of colon and rectal cancers for young versus older patients using a population-based cancer registry. Colon and rectal cancer patients reported in the Surveillance, Epidemiology, and End Results registry (1973-1999) were separately analyzed. Incidence rates over time, stage, and grade were compared for two age groups: young patients (20-40 years, n = 5383) and older patients (60+ years, n = 256,401). For older patients, colon cancer incidence remained stable while rectal cancer incidence decreased 11 per cent to 72.1/100,000 persons (P < 0.05). For the young, colon cancer incidence increased 17 per cent to 2.1 (P < 0.05), and rectal incidence rose 75 per cent to 1.4 (P < 0.05). Young patients had less localized tumors than older patients: colon (25.8{\%} vs. 35.3{\%}, P < 0.001); rectal (38.4{\%} vs. 41.7{\%}, P = 0.005). Young patients also had more poorly differentiated tumors: colon (22.2{\%} vs. 14.7{\%}, P < 0.001); rectal (16.4{\%} vs. 12.3{\%}, P < 0.001). Incidence rates for colon and rectal cancers in young patients are rising, and they have more advanced disease. Although the overall prevalence is low in this population, the increasing incidence suggests health-care providers should have heightened awareness when caring for this population.",
author = "O'Connell, {Jessica B.} and Maggard, {Melinda A.} and Liu, {Jerome H.} and Etzioni, {David A.} and Livingston, {Edward H.} and Clifford Ko",
year = "2003",
language = "English (US)",
volume = "69",
pages = "866--872",
journal = "The American surgeon",
issn = "0003-1348",
publisher = "Southeastern Surgical Congress",
number = "10",

}

TY - JOUR

T1 - Rates of colon and rectal cancers are increasing in young adults

AU - O'Connell, Jessica B.

AU - Maggard, Melinda A.

AU - Liu, Jerome H.

AU - Etzioni, David A.

AU - Livingston, Edward H.

AU - Ko, Clifford

PY - 2003

Y1 - 2003

N2 - Incidence rates for colorectal cancer are decreasing in the United States, possibly due to preventative cancer screening. Because these programs target older patients, their beneficial effects may not apply to young patients. The purpose of this study was to compare incidence rates and tumor characteristics of colon and rectal cancers for young versus older patients using a population-based cancer registry. Colon and rectal cancer patients reported in the Surveillance, Epidemiology, and End Results registry (1973-1999) were separately analyzed. Incidence rates over time, stage, and grade were compared for two age groups: young patients (20-40 years, n = 5383) and older patients (60+ years, n = 256,401). For older patients, colon cancer incidence remained stable while rectal cancer incidence decreased 11 per cent to 72.1/100,000 persons (P < 0.05). For the young, colon cancer incidence increased 17 per cent to 2.1 (P < 0.05), and rectal incidence rose 75 per cent to 1.4 (P < 0.05). Young patients had less localized tumors than older patients: colon (25.8% vs. 35.3%, P < 0.001); rectal (38.4% vs. 41.7%, P = 0.005). Young patients also had more poorly differentiated tumors: colon (22.2% vs. 14.7%, P < 0.001); rectal (16.4% vs. 12.3%, P < 0.001). Incidence rates for colon and rectal cancers in young patients are rising, and they have more advanced disease. Although the overall prevalence is low in this population, the increasing incidence suggests health-care providers should have heightened awareness when caring for this population.

AB - Incidence rates for colorectal cancer are decreasing in the United States, possibly due to preventative cancer screening. Because these programs target older patients, their beneficial effects may not apply to young patients. The purpose of this study was to compare incidence rates and tumor characteristics of colon and rectal cancers for young versus older patients using a population-based cancer registry. Colon and rectal cancer patients reported in the Surveillance, Epidemiology, and End Results registry (1973-1999) were separately analyzed. Incidence rates over time, stage, and grade were compared for two age groups: young patients (20-40 years, n = 5383) and older patients (60+ years, n = 256,401). For older patients, colon cancer incidence remained stable while rectal cancer incidence decreased 11 per cent to 72.1/100,000 persons (P < 0.05). For the young, colon cancer incidence increased 17 per cent to 2.1 (P < 0.05), and rectal incidence rose 75 per cent to 1.4 (P < 0.05). Young patients had less localized tumors than older patients: colon (25.8% vs. 35.3%, P < 0.001); rectal (38.4% vs. 41.7%, P = 0.005). Young patients also had more poorly differentiated tumors: colon (22.2% vs. 14.7%, P < 0.001); rectal (16.4% vs. 12.3%, P < 0.001). Incidence rates for colon and rectal cancers in young patients are rising, and they have more advanced disease. Although the overall prevalence is low in this population, the increasing incidence suggests health-care providers should have heightened awareness when caring for this population.

UR - http://www.scopus.com/inward/record.url?scp=0242348746&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0242348746&partnerID=8YFLogxK

M3 - Article

VL - 69

SP - 866

EP - 872

JO - The American surgeon

JF - The American surgeon

SN - 0003-1348

IS - 10

ER -