Rate of arterial occlusion in patients with acute ischemic stroke

Alexander Y. Zubkov, Hartmut Uschmann, Alejandro Rabinstein

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Objective: Computed tomographic angiography (CTA) was invented more than 20 years ago, but only gained acceptance recently, thanks to advancements in the computer technology. It can demonstrate areas of arterial stenosis or occlusion with accuracy nearly that of digital subtraction angiography (DSA). It is also able to clearly illustrate calcification, which is more difficult to define on magnetic resonance angiography and is not clearly depicted on DSA. Methods: Our retrospective study attempted to clarify the rate of occlusion or stenosis in the patients with acute ischemic stroke. Results: Over the period of 7 months, 93 consecutive patients were admitted with acute ischemic stroke. Fifty-six patients underwent CTA and were included in this study. Most of the patients were admitted after 6 hours following onset of symptoms. There were 28 men and 28 women, and 80.4% of the cohort was of African-American origin. The majority of strokes were attributed to small-vessel disease (25/56). The rest of the cases were deemed secondary to atheroembolism (15/56), cardioembolism (9/56) or of unclear etiology (7/56). In 24 (42.9%) patients, CTA failed to reveal any abnormalities of the cerebrovascular tree. CTA demonstrated arterial occlusion in ten (17.9%) patients and stenosis of extracranial or intracranial arteries on the symptomatic side in 22 (39.2%) patients. There was very good correlation between CTA and ultrasound techniques (carotid duplex and transcranial Doppler). CTA was superior in demonstrating distal intracranial stenosis. Conclusion: Overall, CTA is an extremely valuable and fast way to emergently evaluate the cerebrovascular anatomy, making it very useful for pre-thrombolysis evaluation of patients with ischemic stroke.

Original languageEnglish (US)
Pages (from-to)835-838
Number of pages4
JournalNeurological Research
Volume30
Issue number8
DOIs
StatePublished - Oct 1 2008

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Stroke
Angiography
Pathologic Constriction
Digital Subtraction Angiography
Cholesterol Embolism
Magnetic Resonance Angiography
African Americans
Anatomy
Retrospective Studies
Arteries
Technology

Keywords

  • CTA
  • Occlusion
  • Stroke

ASJC Scopus subject areas

  • Neurology
  • Clinical Neurology

Cite this

Rate of arterial occlusion in patients with acute ischemic stroke. / Zubkov, Alexander Y.; Uschmann, Hartmut; Rabinstein, Alejandro.

In: Neurological Research, Vol. 30, No. 8, 01.10.2008, p. 835-838.

Research output: Contribution to journalArticle

Zubkov, Alexander Y. ; Uschmann, Hartmut ; Rabinstein, Alejandro. / Rate of arterial occlusion in patients with acute ischemic stroke. In: Neurological Research. 2008 ; Vol. 30, No. 8. pp. 835-838.
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