RASA contains a polymorphic microsatellite and maps to bovine syntenic group U22 on Chromosome 7q2.4-qter

André Eggen, Sabina Solinas-Toldo, Allan B. Dietz, James E. Womack, Gerald Stranzinger, Ruedi Fries

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Abstract

The bovine gene for the p21ras protein activator (RASA) includes in its 5′ untranslated region a (TG)n repeat. Analysis of this (TG)n repeat by PCR amplification of genomic DNA revealed a four-allele polymorphism. A cDNA probe was used to assign RASA to the region 2.4-qter of bovine Chromosome (Chr) 7 by in situ hybridization. PCR analysis of a panel of somatic hybrid lines allowed the assignment of RASA to the unassigned syntenic group 22 (U22) and thus localizes U22 on Chr 7.

Original languageEnglish (US)
Pages (from-to)559-563
Number of pages5
JournalMammalian Genome
Volume3
Issue number10
DOIs
StatePublished - Oct 1 1992

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ASJC Scopus subject areas

  • Genetics

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