RASA contains a polymorphic microsatellite and maps to bovine syntenic group U22 on Chromosome 7q2.4-qter

André Eggen; Sabina Solinas-Toldo; Allan B. Dietz; James E. Womack; Gerald Stranzinger; Ruedi Fries

doi:10.1007/BF00350621

RASA contains a polymorphic microsatellite and maps to bovine syntenic group U22 on Chromosome 7q2.4-qter

André Eggen, Sabina Solinas-Toldo, Allan B. Dietz, James E. Womack, Gerald Stranzinger, Ruedi Fries

Laboratory Medicine and Pathology

Research output: Contribution to journal › Article › peer-review

13 Scopus citations

Abstract

The bovine gene for the p21^ras protein activator (RASA) includes in its 5′ untranslated region a (TG)_n repeat. Analysis of this (TG)_n repeat by PCR amplification of genomic DNA revealed a four-allele polymorphism. A cDNA probe was used to assign RASA to the region 2.4-qter of bovine Chromosome (Chr) 7 by in situ hybridization. PCR analysis of a panel of somatic hybrid lines allowed the assignment of RASA to the unassigned syntenic group 22 (U22) and thus localizes U22 on Chr 7.

Original language	English (US)
Pages (from-to)	559-563
Number of pages	5
Journal	Mammalian Genome
Volume	3
Issue number	10
DOIs	https://doi.org/10.1007/BF00350621
State	Published - Oct 1992

ASJC Scopus subject areas

Genetics

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title = "RASA contains a polymorphic microsatellite and maps to bovine syntenic group U22 on Chromosome 7q2.4-qter",

abstract = "The bovine gene for the p21ras protein activator (RASA) includes in its 5′ untranslated region a (TG)n repeat. Analysis of this (TG)n repeat by PCR amplification of genomic DNA revealed a four-allele polymorphism. A cDNA probe was used to assign RASA to the region 2.4-qter of bovine Chromosome (Chr) 7 by in situ hybridization. PCR analysis of a panel of somatic hybrid lines allowed the assignment of RASA to the unassigned syntenic group 22 (U22) and thus localizes U22 on Chr 7.",

author = "Andr{\'e} Eggen and Sabina Solinas-Toldo and Dietz, {Allan B.} and Womack, {James E.} and Gerald Stranzinger and Ruedi Fries",

year = "1992",

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T1 - RASA contains a polymorphic microsatellite and maps to bovine syntenic group U22 on Chromosome 7q2.4-qter

AU - Eggen, André

AU - Solinas-Toldo, Sabina

AU - Dietz, Allan B.

AU - Womack, James E.

AU - Stranzinger, Gerald

AU - Fries, Ruedi

PY - 1992/10

Y1 - 1992/10

N2 - The bovine gene for the p21ras protein activator (RASA) includes in its 5′ untranslated region a (TG)n repeat. Analysis of this (TG)n repeat by PCR amplification of genomic DNA revealed a four-allele polymorphism. A cDNA probe was used to assign RASA to the region 2.4-qter of bovine Chromosome (Chr) 7 by in situ hybridization. PCR analysis of a panel of somatic hybrid lines allowed the assignment of RASA to the unassigned syntenic group 22 (U22) and thus localizes U22 on Chr 7.

AB - The bovine gene for the p21ras protein activator (RASA) includes in its 5′ untranslated region a (TG)n repeat. Analysis of this (TG)n repeat by PCR amplification of genomic DNA revealed a four-allele polymorphism. A cDNA probe was used to assign RASA to the region 2.4-qter of bovine Chromosome (Chr) 7 by in situ hybridization. PCR analysis of a panel of somatic hybrid lines allowed the assignment of RASA to the unassigned syntenic group 22 (U22) and thus localizes U22 on Chr 7.

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RASA contains a polymorphic microsatellite and maps to bovine syntenic group U22 on Chromosome 7q2.4-qter

Abstract

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