RASA contains a polymorphic microsatellite and maps to bovine syntenic group U22 on Chromosome 7q2.4-qter

André Eggen, Sabina Solinas-Toldo, Allan B Dietz, James E. Womack, Gerald Stranzinger, Ruedi Fries

Research output: Contribution to journalArticle

13 Citations (Scopus)

Abstract

The bovine gene for the p21ras protein activator (RASA) includes in its 5′ untranslated region a (TG)n repeat. Analysis of this (TG)n repeat by PCR amplification of genomic DNA revealed a four-allele polymorphism. A cDNA probe was used to assign RASA to the region 2.4-qter of bovine Chromosome (Chr) 7 by in situ hybridization. PCR analysis of a panel of somatic hybrid lines allowed the assignment of RASA to the unassigned syntenic group 22 (U22) and thus localizes U22 on Chr 7.

Original languageEnglish (US)
Pages (from-to)559-563
Number of pages5
JournalMammalian Genome
Volume3
Issue number10
DOIs
StatePublished - Oct 1992
Externally publishedYes

Fingerprint

Chromosomes, Human, Pair 7
Microsatellite Repeats
Chromosomes
Polymerase Chain Reaction
5' Untranslated Regions
In Situ Hybridization
Complementary DNA
Alleles
DNA
Proteins

ASJC Scopus subject areas

  • Genetics

Cite this

RASA contains a polymorphic microsatellite and maps to bovine syntenic group U22 on Chromosome 7q2.4-qter. / Eggen, André; Solinas-Toldo, Sabina; Dietz, Allan B; Womack, James E.; Stranzinger, Gerald; Fries, Ruedi.

In: Mammalian Genome, Vol. 3, No. 10, 10.1992, p. 559-563.

Research output: Contribution to journalArticle

Eggen, André ; Solinas-Toldo, Sabina ; Dietz, Allan B ; Womack, James E. ; Stranzinger, Gerald ; Fries, Ruedi. / RASA contains a polymorphic microsatellite and maps to bovine syntenic group U22 on Chromosome 7q2.4-qter. In: Mammalian Genome. 1992 ; Vol. 3, No. 10. pp. 559-563.
@article{d2f4513bf1ca40d4b2876d3b91794723,
title = "RASA contains a polymorphic microsatellite and maps to bovine syntenic group U22 on Chromosome 7q2.4-qter",
abstract = "The bovine gene for the p21ras protein activator (RASA) includes in its 5′ untranslated region a (TG)n repeat. Analysis of this (TG)n repeat by PCR amplification of genomic DNA revealed a four-allele polymorphism. A cDNA probe was used to assign RASA to the region 2.4-qter of bovine Chromosome (Chr) 7 by in situ hybridization. PCR analysis of a panel of somatic hybrid lines allowed the assignment of RASA to the unassigned syntenic group 22 (U22) and thus localizes U22 on Chr 7.",
author = "Andr{\'e} Eggen and Sabina Solinas-Toldo and Dietz, {Allan B} and Womack, {James E.} and Gerald Stranzinger and Ruedi Fries",
year = "1992",
month = "10",
doi = "10.1007/BF00350621",
language = "English (US)",
volume = "3",
pages = "559--563",
journal = "Mammalian Genome",
issn = "0938-8990",
publisher = "Springer New York",
number = "10",

}

TY - JOUR

T1 - RASA contains a polymorphic microsatellite and maps to bovine syntenic group U22 on Chromosome 7q2.4-qter

AU - Eggen, André

AU - Solinas-Toldo, Sabina

AU - Dietz, Allan B

AU - Womack, James E.

AU - Stranzinger, Gerald

AU - Fries, Ruedi

PY - 1992/10

Y1 - 1992/10

N2 - The bovine gene for the p21ras protein activator (RASA) includes in its 5′ untranslated region a (TG)n repeat. Analysis of this (TG)n repeat by PCR amplification of genomic DNA revealed a four-allele polymorphism. A cDNA probe was used to assign RASA to the region 2.4-qter of bovine Chromosome (Chr) 7 by in situ hybridization. PCR analysis of a panel of somatic hybrid lines allowed the assignment of RASA to the unassigned syntenic group 22 (U22) and thus localizes U22 on Chr 7.

AB - The bovine gene for the p21ras protein activator (RASA) includes in its 5′ untranslated region a (TG)n repeat. Analysis of this (TG)n repeat by PCR amplification of genomic DNA revealed a four-allele polymorphism. A cDNA probe was used to assign RASA to the region 2.4-qter of bovine Chromosome (Chr) 7 by in situ hybridization. PCR analysis of a panel of somatic hybrid lines allowed the assignment of RASA to the unassigned syntenic group 22 (U22) and thus localizes U22 on Chr 7.

UR - http://www.scopus.com/inward/record.url?scp=0026621208&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0026621208&partnerID=8YFLogxK

U2 - 10.1007/BF00350621

DO - 10.1007/BF00350621

M3 - Article

VL - 3

SP - 559

EP - 563

JO - Mammalian Genome

JF - Mammalian Genome

SN - 0938-8990

IS - 10

ER -