Rapid rate on quasi-speech tasks in the semantic variant of primary progressive aphasia: A non-motor phenomenon?

Rene L. Utianski; Hugo Botha; Joseph R. Duffy; Heather M. Clark; Peter R. Martin; Alissa M. Butts; Mary M. Machulda; Jennifer L. Whitwell; Keith A. Josephs

doi:10.1121/1.5082210

Rapid rate on quasi-speech tasks in the semantic variant of primary progressive aphasia: A non-motor phenomenon?

Rene L. Utianski, Hugo Botha, Joseph R. Duffy, Heather M. Clark, Peter R. Martin, Alissa M. Butts, Mary M. Machulda, Jennifer L. Whitwell, Keith A. Josephs

Research output: Contribution to journal › Article › peer-review

1 Scopus citations

Abstract

This study examined the rate of producing alternating motion rates, sequential motion rates (SMRs), and repeated words in 27 individuals with the semantic variant of Primary Progressive Aphasia (svPPA). Only the rate of producing SMRs was significantly elevated in svPPA compared to controls. This may be associated with concomitant neuropsychiatric symptoms in svPPA, as correlation analysis showed a relationship between increased SMR rate and the Neuropsychiatric Inventory Questionnaire, which documented anxiety and disinhibition. Future studies will assess these findings in a larger cohort and work to better understand if this phenomenon is a manifestation of behavioral and/or motor changes.

Original language	English (US)
Pages (from-to)	3364-3370
Number of pages	7
Journal	Journal of the Acoustical Society of America
Volume	144
Issue number	6
DOIs	https://doi.org/10.1121/1.5082210
State	Published - Dec 1 2018

ASJC Scopus subject areas

Arts and Humanities (miscellaneous)
Acoustics and Ultrasonics

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title = "Rapid rate on quasi-speech tasks in the semantic variant of primary progressive aphasia: A non-motor phenomenon?",

abstract = "This study examined the rate of producing alternating motion rates, sequential motion rates (SMRs), and repeated words in 27 individuals with the semantic variant of Primary Progressive Aphasia (svPPA). Only the rate of producing SMRs was significantly elevated in svPPA compared to controls. This may be associated with concomitant neuropsychiatric symptoms in svPPA, as correlation analysis showed a relationship between increased SMR rate and the Neuropsychiatric Inventory Questionnaire, which documented anxiety and disinhibition. Future studies will assess these findings in a larger cohort and work to better understand if this phenomenon is a manifestation of behavioral and/or motor changes.",

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AU - Utianski, Rene L.

AU - Botha, Hugo

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AU - Clark, Heather M.

AU - Martin, Peter R.

AU - Butts, Alissa M.

AU - Machulda, Mary M.

AU - Whitwell, Jennifer L.

AU - Josephs, Keith A.

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Rapid rate on quasi-speech tasks in the semantic variant of primary progressive aphasia: A non-motor phenomenon?

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