Abstract
Rapid MR elastography (MRE) techniques using spatially-selective excitations to reduce acquisition times to a few seconds or less were devised and tested. The techniques included reduced field of view (rFOV) MRE and 1D MRE (beam MRE) using 2D spatially selective RF excitations for gradient-echo (GRE) applications and intersecting 90° and 180° slice-selective excitations for spin-echo (SE) applications. It was shown that scan times could be reduced by a factor of 8 using rFOV MRE, and by 64 using beam MRE, while still obtaining stiffness estimates comparable to full-FOV MRE. Results were shown in gel phantom experiments as well as in the case of a preserved postmortem breast tissue specimen with a stiff lesion. These methods can be used to more rapidly interrogate regions of interest (ROIs) in tissue to quickly obtain information about the viscoelastic properties of that tissue.
Original language | English (US) |
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Pages (from-to) | 1381-1389 |
Number of pages | 9 |
Journal | Magnetic Resonance in Medicine |
Volume | 55 |
Issue number | 6 |
DOIs | |
State | Published - Jun 2006 |
Keywords
- Beam elastography
- Magnetic resonance elastography
- Reduced FOV
- Selective excitation
- Tissue characterization
ASJC Scopus subject areas
- Radiology Nuclear Medicine and imaging