Radiotherapy does not impact long-term function following resection of soft-tissue sarcomas of the hand

Nicholas F. Munaretto, Anthony L. Logli, Peter S. Rose, Ivy A. Petersen, Safia K. Ahmed, Karim Bakri, Steven L. Moran, Matthew T. Houdek

Research output: Contribution to journalArticlepeer-review

Abstract

Background/Aim: Radiotherapy for soft tissue sarcomas (STS) of the hand is thought to be associated with poor function. The aim of this study was to compare the long-term functional outcome in patients with and without radiotherapy. Patients and Methods: At long-term follow-up (mean 10±5 years), 33 (13 males, 20 female) patients, were alive for review. The mean patient age at surgery was 33±17 years and 13 (39%) patients received radiotherapy (mean dose 55±6 Gy). Results: Postoperatively, the mean QuickDASH and MSTS93 were 7±8 and 92±8%, respectively. Comparing patients with and without radiotherapy, there was no difference (p>0.05) between the mean QuickDASH (5±5 vs. 8±9) or MSTS93 (93±9% vs. 91±8%). Surgical complication occurred more commonly in patients with radiotherapy (46% vs. 15%, p=0.10). Conclusion: The use of radiotherapy was associated with a higher rate of complications, however, was not associated with a worse long-term functional outcome in patients with hand STS.

Original languageEnglish (US)
Pages (from-to)1463-1466
Number of pages4
JournalAnticancer research
Volume40
Issue number3
DOIs
StatePublished - Jan 1 2020

Keywords

  • Hand
  • Outcome
  • Radiotherapy
  • Soft tissue sarcoma

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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