Radiologic Considerations and Standardization of Malignant Pleural Mesothelioma Imaging Within Clinical Trials: Consensus Statement from the NCI Thoracic Malignancy Steering Committee – International Association for the Study of Lung Cancer – Mesothelioma Applied Research Foundation Clinical Trials Planning Meeting

Ritu R. Gill, Anne S. Tsao, Hedy L. Kindler, William G. Richards, Samuel G. Armato, Roslyn J. Francis, Daniel R. Gomez, Suzanne Dahlberg, Andreas Rimner, Charles B. Simone, Marc de Perrot, Gideon Blumenthal, Alex A. Adjei, Raphael Bueno, David H. Harpole, Mary Hesdorffer, Fred R. Hirsch, Harvey I. Pass, Ellen Yorke, Kenneth RosenzweigBryan Burt, Dean A. Fennell, Wolf Lindwasser, Shakun Malik, Tobias Peikert, Aaron S. Mansfield, Ravi Salgia, Haining Yang, Valerie W. Rusch, Anna K. Nowak

Research output: Contribution to journalArticlepeer-review

1 Scopus citations

Abstract

Detailed guidelines pertaining to radiological assessment of malignant pleural mesothelioma are currently lacking due to the rarity of the disease, complex morphology, propensity to invade multiple planes simultaneously, and lack of specific recommendations within the radiology community about assessment, reporting, and follow-up. In March 2017, a multidisciplinary meeting of mesothelioma experts was co-sponsored by the National Cancer Institute Thoracic Malignancy Steering Committee, International Association for the Study of Lung Cancer, and the Mesothelioma Applied Research Foundation. One of the outcomes of this conference was the foundation of detailed, multidisciplinary consensus imaging and management guidelines. Here, we present the recommendations for radiologic assessment of malignant pleural mesothelioma in the setting of clinical trial enrollment. We discuss optimization of imaging parameters across modalities, standardized reporting, and response assessment within clinical trials.

Original languageEnglish (US)
Pages (from-to)1718-1731
Number of pages14
JournalJournal of Thoracic Oncology
Volume14
Issue number10
DOIs
StatePublished - Oct 2019

ASJC Scopus subject areas

  • Oncology
  • Pulmonary and Respiratory Medicine

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