Radiographic findings in 32 cases of primary CNS lymphoma

Clifford R Jr. Jack, D. F. Reese, B. W. Scheithauer

Research output: Contribution to journalArticle

61 Citations (Scopus)

Abstract

Computed tomographic (CT) or angiographic (or both) findings were analyzed in 32 cases of pathologically proved primary non-Hodgkin lymphoma of the central nervous system. CT scans were available in 28 of the 32 cases. Thirty lesions were found in the 28 cases. In comparison with previous literature, the frequency of involvement of deep central structures (30%), multiple lesions (11%), and subependymal lesions (4%) was lower and that of lesions in the periphery of the supratentorial compartment was higher (46%). In agreement with previous literature, most of the lesions were of increased density (63%), enhanced (100%), and enhanced homogeneously (71%). Twenty-nine of the 32 patients underwent cerebral angiography. In 12 patients, a homogeneous vascular stain was found that appeared in the late arterial or early venous phase and had a meningiomalike pattern. This staining pattern has not been emphasized sufficiently in previous literature. It was believed that such an angiographic pattern in a dense, homogeneously enhancing parenchymal lesion is suggestive of a primary lymphoma of the central nervous system. Magnetic resonance imaging was performed in one patient with two lesions, and both lesions demonstrated prolonged T2 relaxation times.

Original languageEnglish (US)
Pages (from-to)271-276
Number of pages6
JournalAmerican Journal of Roentgenology
Volume146
Issue number2
StatePublished - 1986

Fingerprint

Lymphoma
Central Nervous System
Cerebral Angiography
Non-Hodgkin's Lymphoma
Blood Vessels
Coloring Agents
Magnetic Resonance Imaging
Staining and Labeling

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging
  • Radiological and Ultrasound Technology

Cite this

Radiographic findings in 32 cases of primary CNS lymphoma. / Jack, Clifford R Jr.; Reese, D. F.; Scheithauer, B. W.

In: American Journal of Roentgenology, Vol. 146, No. 2, 1986, p. 271-276.

Research output: Contribution to journalArticle

Jack, CRJ, Reese, DF & Scheithauer, BW 1986, 'Radiographic findings in 32 cases of primary CNS lymphoma', American Journal of Roentgenology, vol. 146, no. 2, pp. 271-276.
Jack, Clifford R Jr. ; Reese, D. F. ; Scheithauer, B. W. / Radiographic findings in 32 cases of primary CNS lymphoma. In: American Journal of Roentgenology. 1986 ; Vol. 146, No. 2. pp. 271-276.
@article{32331d829626444b9cf8a935a68e8711,
title = "Radiographic findings in 32 cases of primary CNS lymphoma",
abstract = "Computed tomographic (CT) or angiographic (or both) findings were analyzed in 32 cases of pathologically proved primary non-Hodgkin lymphoma of the central nervous system. CT scans were available in 28 of the 32 cases. Thirty lesions were found in the 28 cases. In comparison with previous literature, the frequency of involvement of deep central structures (30{\%}), multiple lesions (11{\%}), and subependymal lesions (4{\%}) was lower and that of lesions in the periphery of the supratentorial compartment was higher (46{\%}). In agreement with previous literature, most of the lesions were of increased density (63{\%}), enhanced (100{\%}), and enhanced homogeneously (71{\%}). Twenty-nine of the 32 patients underwent cerebral angiography. In 12 patients, a homogeneous vascular stain was found that appeared in the late arterial or early venous phase and had a meningiomalike pattern. This staining pattern has not been emphasized sufficiently in previous literature. It was believed that such an angiographic pattern in a dense, homogeneously enhancing parenchymal lesion is suggestive of a primary lymphoma of the central nervous system. Magnetic resonance imaging was performed in one patient with two lesions, and both lesions demonstrated prolonged T2 relaxation times.",
author = "Jack, {Clifford R Jr.} and Reese, {D. F.} and Scheithauer, {B. W.}",
year = "1986",
language = "English (US)",
volume = "146",
pages = "271--276",
journal = "American Journal of Roentgenology",
issn = "0361-803X",
publisher = "American Roentgen Ray Society",
number = "2",

}

TY - JOUR

T1 - Radiographic findings in 32 cases of primary CNS lymphoma

AU - Jack, Clifford R Jr.

AU - Reese, D. F.

AU - Scheithauer, B. W.

PY - 1986

Y1 - 1986

N2 - Computed tomographic (CT) or angiographic (or both) findings were analyzed in 32 cases of pathologically proved primary non-Hodgkin lymphoma of the central nervous system. CT scans were available in 28 of the 32 cases. Thirty lesions were found in the 28 cases. In comparison with previous literature, the frequency of involvement of deep central structures (30%), multiple lesions (11%), and subependymal lesions (4%) was lower and that of lesions in the periphery of the supratentorial compartment was higher (46%). In agreement with previous literature, most of the lesions were of increased density (63%), enhanced (100%), and enhanced homogeneously (71%). Twenty-nine of the 32 patients underwent cerebral angiography. In 12 patients, a homogeneous vascular stain was found that appeared in the late arterial or early venous phase and had a meningiomalike pattern. This staining pattern has not been emphasized sufficiently in previous literature. It was believed that such an angiographic pattern in a dense, homogeneously enhancing parenchymal lesion is suggestive of a primary lymphoma of the central nervous system. Magnetic resonance imaging was performed in one patient with two lesions, and both lesions demonstrated prolonged T2 relaxation times.

AB - Computed tomographic (CT) or angiographic (or both) findings were analyzed in 32 cases of pathologically proved primary non-Hodgkin lymphoma of the central nervous system. CT scans were available in 28 of the 32 cases. Thirty lesions were found in the 28 cases. In comparison with previous literature, the frequency of involvement of deep central structures (30%), multiple lesions (11%), and subependymal lesions (4%) was lower and that of lesions in the periphery of the supratentorial compartment was higher (46%). In agreement with previous literature, most of the lesions were of increased density (63%), enhanced (100%), and enhanced homogeneously (71%). Twenty-nine of the 32 patients underwent cerebral angiography. In 12 patients, a homogeneous vascular stain was found that appeared in the late arterial or early venous phase and had a meningiomalike pattern. This staining pattern has not been emphasized sufficiently in previous literature. It was believed that such an angiographic pattern in a dense, homogeneously enhancing parenchymal lesion is suggestive of a primary lymphoma of the central nervous system. Magnetic resonance imaging was performed in one patient with two lesions, and both lesions demonstrated prolonged T2 relaxation times.

UR - http://www.scopus.com/inward/record.url?scp=0022619250&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0022619250&partnerID=8YFLogxK

M3 - Article

C2 - 3484575

AN - SCOPUS:0022619250

VL - 146

SP - 271

EP - 276

JO - American Journal of Roentgenology

JF - American Journal of Roentgenology

SN - 0361-803X

IS - 2

ER -