Radiofrequency ablation for total Barrett's eradication: a description of the endoscopic technique, its clinical results and future prospects.

R. E. Pouw, V. K. Sharma, J. J. Bergman, D. E. Fleischer

Research output: Contribution to journalArticle

38 Citations (Scopus)

Abstract

Stepwise circumferential and focal radiofrequency ablation using the HALO system is a novel and promising ablative modality for Barrett's esophagus. Primary circumferential ablation is performed using a balloon-based bipolar electrode, while secondary treatment of residual Barrett's epithelium is performed using an endoscope-mounted bipolar electrode on an articulated platform. It has been used as a single-modality treatment or in combination with other therapies. Recent studies suggest that this ablation technique is highly effective in removing Barrett's mucosa and its associated dysplasia without the known drawbacks of photodynamic therapy or argon plasma coagulation, such as esophageal stenosis and subsquamous foci of intestinal metaplasia (also known as "buried Barrett"). [nl]In this review paper we will explain the technical background of radiofrequency ablation using the HALO system, give a summary of its current status, and speculate on possible future applications.

Original languageEnglish (US)
Pages (from-to)1033-1040
Number of pages8
JournalEndoscopy
Volume40
Issue number12
StatePublished - Dec 2008
Externally publishedYes

Fingerprint

Barrett Esophagus
Electrodes
Argon Plasma Coagulation
Ablation Techniques
Esophageal Stenosis
Endoscopes
Photochemotherapy
Metaplasia
Mucous Membrane
Therapeutics

ASJC Scopus subject areas

  • Gastroenterology

Cite this

Radiofrequency ablation for total Barrett's eradication : a description of the endoscopic technique, its clinical results and future prospects. / Pouw, R. E.; Sharma, V. K.; Bergman, J. J.; Fleischer, D. E.

In: Endoscopy, Vol. 40, No. 12, 12.2008, p. 1033-1040.

Research output: Contribution to journalArticle

Pouw, R. E. ; Sharma, V. K. ; Bergman, J. J. ; Fleischer, D. E. / Radiofrequency ablation for total Barrett's eradication : a description of the endoscopic technique, its clinical results and future prospects. In: Endoscopy. 2008 ; Vol. 40, No. 12. pp. 1033-1040.
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