Radioactive seed localization for breast conservation surgery: Low positive margin rate with no learning curve

Cristine S. Velazco, Nabil Wasif, Barbara A Pockaj, Richard J. Gray

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

Background: Radioactive seed localization (RSL) is an alternative to wire localization. We compared the rate of positive margins for evidence of a learning curve in implementing RSL. Methods: A retrospective review of RSL by three surgeons at a single institution from 2002 to 2016. Positive margins were defined as ink on tumor. Results: Surgeon experience with RSL for ranged from 142 to >500 cases. The positive margin rate among the first 100 of each surgeons' experience (n = 300) was 2.3% and the rate during the most recent up to 100 cases after experience with at least 100 RSL procedures (n = 242) was 4.1% (p = 0.32). Individual surgeon's positive margin rates ranged from 2 to 5% in the early experience and 2-7% in the later experience (p = NS). Conclusions: RSL for breast conservation surgery has a low rate of positive margins even early in a surgeon's experience. Implementation of RSL can be done with no evidence of a learning curve. Summary: Radioactive seed localization is an alternative to wire localization for breast conservation surgery. No learning curve, as defined by the rate of positive margins, was found for this study, indicating the technique is easily learned by breast cancer surgeons.

Original languageEnglish (US)
JournalAmerican Journal of Surgery
DOIs
StateAccepted/In press - 2017

Fingerprint

Learning Curve
Seeds
Breast
Ink
Surgeons
Breast Neoplasms

Keywords

  • Breast conserving therapy
  • Learning curve
  • Positive margin
  • Seed localization

ASJC Scopus subject areas

  • Surgery

Cite this

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title = "Radioactive seed localization for breast conservation surgery: Low positive margin rate with no learning curve",
abstract = "Background: Radioactive seed localization (RSL) is an alternative to wire localization. We compared the rate of positive margins for evidence of a learning curve in implementing RSL. Methods: A retrospective review of RSL by three surgeons at a single institution from 2002 to 2016. Positive margins were defined as ink on tumor. Results: Surgeon experience with RSL for ranged from 142 to >500 cases. The positive margin rate among the first 100 of each surgeons' experience (n = 300) was 2.3{\%} and the rate during the most recent up to 100 cases after experience with at least 100 RSL procedures (n = 242) was 4.1{\%} (p = 0.32). Individual surgeon's positive margin rates ranged from 2 to 5{\%} in the early experience and 2-7{\%} in the later experience (p = NS). Conclusions: RSL for breast conservation surgery has a low rate of positive margins even early in a surgeon's experience. Implementation of RSL can be done with no evidence of a learning curve. Summary: Radioactive seed localization is an alternative to wire localization for breast conservation surgery. No learning curve, as defined by the rate of positive margins, was found for this study, indicating the technique is easily learned by breast cancer surgeons.",
keywords = "Breast conserving therapy, Learning curve, Positive margin, Seed localization",
author = "Velazco, {Cristine S.} and Nabil Wasif and Pockaj, {Barbara A} and Gray, {Richard J.}",
year = "2017",
doi = "10.1016/j.amjsurg.2017.08.025",
language = "English (US)",
journal = "American Journal of Surgery",
issn = "0002-9610",
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TY - JOUR

T1 - Radioactive seed localization for breast conservation surgery

T2 - Low positive margin rate with no learning curve

AU - Velazco, Cristine S.

AU - Wasif, Nabil

AU - Pockaj, Barbara A

AU - Gray, Richard J.

PY - 2017

Y1 - 2017

N2 - Background: Radioactive seed localization (RSL) is an alternative to wire localization. We compared the rate of positive margins for evidence of a learning curve in implementing RSL. Methods: A retrospective review of RSL by three surgeons at a single institution from 2002 to 2016. Positive margins were defined as ink on tumor. Results: Surgeon experience with RSL for ranged from 142 to >500 cases. The positive margin rate among the first 100 of each surgeons' experience (n = 300) was 2.3% and the rate during the most recent up to 100 cases after experience with at least 100 RSL procedures (n = 242) was 4.1% (p = 0.32). Individual surgeon's positive margin rates ranged from 2 to 5% in the early experience and 2-7% in the later experience (p = NS). Conclusions: RSL for breast conservation surgery has a low rate of positive margins even early in a surgeon's experience. Implementation of RSL can be done with no evidence of a learning curve. Summary: Radioactive seed localization is an alternative to wire localization for breast conservation surgery. No learning curve, as defined by the rate of positive margins, was found for this study, indicating the technique is easily learned by breast cancer surgeons.

AB - Background: Radioactive seed localization (RSL) is an alternative to wire localization. We compared the rate of positive margins for evidence of a learning curve in implementing RSL. Methods: A retrospective review of RSL by three surgeons at a single institution from 2002 to 2016. Positive margins were defined as ink on tumor. Results: Surgeon experience with RSL for ranged from 142 to >500 cases. The positive margin rate among the first 100 of each surgeons' experience (n = 300) was 2.3% and the rate during the most recent up to 100 cases after experience with at least 100 RSL procedures (n = 242) was 4.1% (p = 0.32). Individual surgeon's positive margin rates ranged from 2 to 5% in the early experience and 2-7% in the later experience (p = NS). Conclusions: RSL for breast conservation surgery has a low rate of positive margins even early in a surgeon's experience. Implementation of RSL can be done with no evidence of a learning curve. Summary: Radioactive seed localization is an alternative to wire localization for breast conservation surgery. No learning curve, as defined by the rate of positive margins, was found for this study, indicating the technique is easily learned by breast cancer surgeons.

KW - Breast conserving therapy

KW - Learning curve

KW - Positive margin

KW - Seed localization

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