Radiation therapy strategies for skull-base malignancies

J. D. Palmer; M. E. Gamez; K. Ranta; H. Ruiz-Garcia; J. L. Peterson; D. M. Blakaj; D. Prevedello; R. Carrau; A. Mahajan; K. L. Chaichana; D. M. Trifiletti

doi:10.1007/s11060-020-03569-7

Radiation therapy strategies for skull-base malignancies

J. D. Palmer, M. E. Gamez, K. Ranta, H. Ruiz-Garcia, J. L. Peterson, D. M. Blakaj, D. Prevedello, R. Carrau, A. Mahajan, K. L. Chaichana, D. M. Trifiletti

Radiation Oncology

Research output: Contribution to journal › Review article › peer-review

1 Scopus citations

Abstract

Introduction: The management of skull base malignancies continues to evolve with improvements in surgical technique, advances in radiation delivery and novel systemic agents. Methods: In this review, we aim to discuss in detail the management of common skull base pathologies which typically require multimodality therapy, focusing on the radiotherapeutic aspects of care. Results: Technological advances in the administration of radiation therapy have led to a wide variety of different treatment strategies for the treatment of skull base malignances, with outcomes summarized herein. Conclusion: Radiation treatment plays a key and critical role in the management of patients with skull base tumors. Recent advancements continue to improve the risk/benefit ratio for radiotherapy in this setting.

Original language	English (US)
Pages (from-to)	445-462
Number of pages	18
Journal	Journal of neuro-oncology
Volume	150
Issue number	3
DOIs	https://doi.org/10.1007/s11060-020-03569-7
State	Published - Dec 2020

Keywords

Gamma knife radiosurgery
Intensity modulated proton therapy
Intensity modulated radiation therapy
Proton therapy
Radiation
Skull base
Stereotactic radiosurgery

ASJC Scopus subject areas

Oncology
Neurology
Clinical Neurology
Cancer Research

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10.1007/s11060-020-03569-7

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title = "Radiation therapy strategies for skull-base malignancies",

abstract = "Introduction: The management of skull base malignancies continues to evolve with improvements in surgical technique, advances in radiation delivery and novel systemic agents. Methods: In this review, we aim to discuss in detail the management of common skull base pathologies which typically require multimodality therapy, focusing on the radiotherapeutic aspects of care. Results: Technological advances in the administration of radiation therapy have led to a wide variety of different treatment strategies for the treatment of skull base malignances, with outcomes summarized herein. Conclusion: Radiation treatment plays a key and critical role in the management of patients with skull base tumors. Recent advancements continue to improve the risk/benefit ratio for radiotherapy in this setting.",

keywords = "Gamma knife radiosurgery, Intensity modulated proton therapy, Intensity modulated radiation therapy, Proton therapy, Radiation, Skull base, Stereotactic radiosurgery",

author = "Palmer, {J. D.} and Gamez, {M. E.} and K. Ranta and H. Ruiz-Garcia and Peterson, {J. L.} and Blakaj, {D. M.} and D. Prevedello and R. Carrau and A. Mahajan and Chaichana, {K. L.} and Trifiletti, {D. M.}",

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year = "2020",

month = dec,

doi = "10.1007/s11060-020-03569-7",

language = "English (US)",

volume = "150",

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AU - Palmer, J. D.

AU - Gamez, M. E.

AU - Ranta, K.

AU - Ruiz-Garcia, H.

AU - Peterson, J. L.

AU - Blakaj, D. M.

AU - Prevedello, D.

AU - Carrau, R.

AU - Mahajan, A.

AU - Chaichana, K. L.

AU - Trifiletti, D. M.

PY - 2020/12

Y1 - 2020/12

N2 - Introduction: The management of skull base malignancies continues to evolve with improvements in surgical technique, advances in radiation delivery and novel systemic agents. Methods: In this review, we aim to discuss in detail the management of common skull base pathologies which typically require multimodality therapy, focusing on the radiotherapeutic aspects of care. Results: Technological advances in the administration of radiation therapy have led to a wide variety of different treatment strategies for the treatment of skull base malignances, with outcomes summarized herein. Conclusion: Radiation treatment plays a key and critical role in the management of patients with skull base tumors. Recent advancements continue to improve the risk/benefit ratio for radiotherapy in this setting.

AB - Introduction: The management of skull base malignancies continues to evolve with improvements in surgical technique, advances in radiation delivery and novel systemic agents. Methods: In this review, we aim to discuss in detail the management of common skull base pathologies which typically require multimodality therapy, focusing on the radiotherapeutic aspects of care. Results: Technological advances in the administration of radiation therapy have led to a wide variety of different treatment strategies for the treatment of skull base malignances, with outcomes summarized herein. Conclusion: Radiation treatment plays a key and critical role in the management of patients with skull base tumors. Recent advancements continue to improve the risk/benefit ratio for radiotherapy in this setting.

KW - Gamma knife radiosurgery

KW - Intensity modulated proton therapy

KW - Intensity modulated radiation therapy

KW - Proton therapy

KW - Radiation

KW - Skull base

KW - Stereotactic radiosurgery

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JO - Journal of neuro-oncology

JF - Journal of neuro-oncology

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ER -

Radiation therapy strategies for skull-base malignancies

Abstract

Keywords

ASJC Scopus subject areas

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