Radiation-Induced Laryngeal Mucous Membrane Pemphigoid

Amit Syal, David G. Lott, William E. Karle

Research output: Contribution to journalArticlepeer-review

Abstract

Objectives: Bullous pemphigoid has previously been linked to radiotherapy, but here we report the first case of MMP suspected to be a consequence of RT. Methods: The patient described is an 85-year-old male who underwent RT to treat squamous cell carcinoma of the palatine tonsil. Shortly after therapy, the patient developed blisters with worsening dyspnea and dysphonia. Results: This patient was successfully treated with a combination of oral immunosuppressants and surgical intervention. Conclusion: This incident underscores that not all episodes of mucosal ulceration following radiation are a result of mucositis and MMP should be considered in the differential. Level of evidence: Level 4.

Original languageEnglish (US)
JournalAnnals of Otology, Rhinology and Laryngology
DOIs
StateAccepted/In press - 2022

Keywords

  • bullous pemphigoid
  • mucous membrane pemphigoid
  • radiation therapy
  • supraglottic stenosis

ASJC Scopus subject areas

  • Otorhinolaryngology

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