Quantitative assessment of pulmonary perfusion with dynamic contrast- enhanced MRI

Hiroto Hatabu; Eiji Tadamura; David L. Levin; Qun Chen; Wei Li; Ducksoo Kim; Pottumarthi V. Prasad; Robert R. Edelman

doi:10.1002/(SICI)1522-2594(199912)42:6<1033::AID-MRM7>3.0.CO;2-7

Quantitative assessment of pulmonary perfusion with dynamic contrast- enhanced MRI

Hiroto Hatabu, Eiji Tadamura, David L. Levin, Qun Chen, Wei Li, Ducksoo Kim, Pottumarthi V. Prasad, Robert R. Edelman

Radiology

Research output: Contribution to journal › Article › peer-review

159 Scopus citations

Abstract

The feasibility of qualitative assessment of pulmonary perfusion using dynamic contrast enhanced MRI with ultra-short TE has recently been demonstrated. In the current study, quantitative analysis was attempted based on the indicator dilution principle using a pig model of pulmonary embolism. The results were compared with the absolute pulmonary perfusion obtained with colored microspheres. The inverse of apparent mean transit time (1/τ(app)), distribution volume (V), and V/τ(app) were correlated well with the absolute lung perfusion. This study demonstrates that MR has the potential to evaluate pulmonary perfusion quantitatively.

Original language	English (US)
Pages (from-to)	1033-1038
Number of pages	6
Journal	Magnetic Resonance in Medicine
Volume	42
Issue number	6
DOIs	https://doi.org/10.1002/(SICI)1522-2594(199912)42:6<1033::AID-MRM7>3.0.CO;2-7
State	Published - 1999

Keywords

Lung, perfusion
Magnetic resonance
Pulmonary artery

ASJC Scopus subject areas

Radiology Nuclear Medicine and imaging

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10.1002/(SICI)1522-2594(199912)42:6<1033::AID-MRM7>3.0.CO;2-7

Cite this

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title = "Quantitative assessment of pulmonary perfusion with dynamic contrast- enhanced MRI",

abstract = "The feasibility of qualitative assessment of pulmonary perfusion using dynamic contrast enhanced MRI with ultra-short TE has recently been demonstrated. In the current study, quantitative analysis was attempted based on the indicator dilution principle using a pig model of pulmonary embolism. The results were compared with the absolute pulmonary perfusion obtained with colored microspheres. The inverse of apparent mean transit time (1/τ(app)), distribution volume (V), and V/τ(app) were correlated well with the absolute lung perfusion. This study demonstrates that MR has the potential to evaluate pulmonary perfusion quantitatively.",

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T1 - Quantitative assessment of pulmonary perfusion with dynamic contrast- enhanced MRI

AU - Hatabu, Hiroto

AU - Tadamura, Eiji

AU - Levin, David L.

AU - Chen, Qun

AU - Li, Wei

AU - Kim, Ducksoo

AU - Prasad, Pottumarthi V.

AU - Edelman, Robert R.

PY - 1999

Y1 - 1999

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AB - The feasibility of qualitative assessment of pulmonary perfusion using dynamic contrast enhanced MRI with ultra-short TE has recently been demonstrated. In the current study, quantitative analysis was attempted based on the indicator dilution principle using a pig model of pulmonary embolism. The results were compared with the absolute pulmonary perfusion obtained with colored microspheres. The inverse of apparent mean transit time (1/τ(app)), distribution volume (V), and V/τ(app) were correlated well with the absolute lung perfusion. This study demonstrates that MR has the potential to evaluate pulmonary perfusion quantitatively.

KW - Lung, perfusion

KW - Magnetic resonance

KW - Pulmonary artery

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Quantitative assessment of pulmonary perfusion with dynamic contrast- enhanced MRI

Abstract

Keywords

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