Quantitative analysis of renal vascularization in fetuses with urinary tract obstruction by three-dimensional power-Doppler

Lisandra Stein Bernardes, Rossana P.V. Francisco, Julien Saada, Remi Salomon, Rodrigo Ruano, Stephen Lortad-Jacob, Marcelo Zugaib, Alexandra Benachi

Research output: Contribution to journalArticle

8 Citations (Scopus)

Abstract

Objective: To evaluate the applicability of 3-dimensional evaluation of renal vascularization for predicting postnatal renal function in fetuses with suspected urinary obstruction. Study Design: Fetuses were evaluated by 3-dimensional power-Doppler histogram, and vascular indices were estimated. Depth between the probe and the renal cortex was also evaluated. Postnatal follow-up was obtained in all cases and the main outcome was renal impairment. Results: Twenty-three fetuses with urinary dilatation (cases) and 73 with normal renal morphology (controls) were included in the current study. Five (21.7%) cases developed renal impairment. Vascularization index and vascularization and flow index were significantly lower in fetuses that developed renal impairment compared with those with normal renal function (P =.009 and P =.036, respectively). The 3 vascular indexes correlated with depth. Percentage of depth-corrected vascularization index and vascularization flow index were lower in fetuses developing postnatal renal failure. Conclusion: Fetal renal vascularity (vascularization index and vascularization and flow index) was significantly lower in fetuses that developed renal impairment.

Original languageEnglish (US)
JournalAmerican Journal of Obstetrics and Gynecology
Volume205
Issue number6
DOIs
StatePublished - Dec 1 2011
Externally publishedYes

Fingerprint

Urinary Tract
Fetus
Kidney
Blood Vessels
Renal Insufficiency
Dilatation

Keywords

  • 3-dimensional ultrasound
  • fetus
  • kidney
  • prenatal diagnosis
  • renal function

ASJC Scopus subject areas

  • Obstetrics and Gynecology

Cite this

Quantitative analysis of renal vascularization in fetuses with urinary tract obstruction by three-dimensional power-Doppler. / Bernardes, Lisandra Stein; Francisco, Rossana P.V.; Saada, Julien; Salomon, Remi; Ruano, Rodrigo; Lortad-Jacob, Stephen; Zugaib, Marcelo; Benachi, Alexandra.

In: American Journal of Obstetrics and Gynecology, Vol. 205, No. 6, 01.12.2011.

Research output: Contribution to journalArticle

Bernardes, Lisandra Stein ; Francisco, Rossana P.V. ; Saada, Julien ; Salomon, Remi ; Ruano, Rodrigo ; Lortad-Jacob, Stephen ; Zugaib, Marcelo ; Benachi, Alexandra. / Quantitative analysis of renal vascularization in fetuses with urinary tract obstruction by three-dimensional power-Doppler. In: American Journal of Obstetrics and Gynecology. 2011 ; Vol. 205, No. 6.
@article{6f4027e199874894a3e1b4b19375042c,
title = "Quantitative analysis of renal vascularization in fetuses with urinary tract obstruction by three-dimensional power-Doppler",
abstract = "Objective: To evaluate the applicability of 3-dimensional evaluation of renal vascularization for predicting postnatal renal function in fetuses with suspected urinary obstruction. Study Design: Fetuses were evaluated by 3-dimensional power-Doppler histogram, and vascular indices were estimated. Depth between the probe and the renal cortex was also evaluated. Postnatal follow-up was obtained in all cases and the main outcome was renal impairment. Results: Twenty-three fetuses with urinary dilatation (cases) and 73 with normal renal morphology (controls) were included in the current study. Five (21.7{\%}) cases developed renal impairment. Vascularization index and vascularization and flow index were significantly lower in fetuses that developed renal impairment compared with those with normal renal function (P =.009 and P =.036, respectively). The 3 vascular indexes correlated with depth. Percentage of depth-corrected vascularization index and vascularization flow index were lower in fetuses developing postnatal renal failure. Conclusion: Fetal renal vascularity (vascularization index and vascularization and flow index) was significantly lower in fetuses that developed renal impairment.",
keywords = "3-dimensional ultrasound, fetus, kidney, prenatal diagnosis, renal function",
author = "Bernardes, {Lisandra Stein} and Francisco, {Rossana P.V.} and Julien Saada and Remi Salomon and Rodrigo Ruano and Stephen Lortad-Jacob and Marcelo Zugaib and Alexandra Benachi",
year = "2011",
month = "12",
day = "1",
doi = "10.1016/j.ajog.2011.06.063",
language = "English (US)",
volume = "205",
journal = "American Journal of Obstetrics and Gynecology",
issn = "0002-9378",
publisher = "Mosby Inc.",
number = "6",

}

TY - JOUR

T1 - Quantitative analysis of renal vascularization in fetuses with urinary tract obstruction by three-dimensional power-Doppler

AU - Bernardes, Lisandra Stein

AU - Francisco, Rossana P.V.

AU - Saada, Julien

AU - Salomon, Remi

AU - Ruano, Rodrigo

AU - Lortad-Jacob, Stephen

AU - Zugaib, Marcelo

AU - Benachi, Alexandra

PY - 2011/12/1

Y1 - 2011/12/1

N2 - Objective: To evaluate the applicability of 3-dimensional evaluation of renal vascularization for predicting postnatal renal function in fetuses with suspected urinary obstruction. Study Design: Fetuses were evaluated by 3-dimensional power-Doppler histogram, and vascular indices were estimated. Depth between the probe and the renal cortex was also evaluated. Postnatal follow-up was obtained in all cases and the main outcome was renal impairment. Results: Twenty-three fetuses with urinary dilatation (cases) and 73 with normal renal morphology (controls) were included in the current study. Five (21.7%) cases developed renal impairment. Vascularization index and vascularization and flow index were significantly lower in fetuses that developed renal impairment compared with those with normal renal function (P =.009 and P =.036, respectively). The 3 vascular indexes correlated with depth. Percentage of depth-corrected vascularization index and vascularization flow index were lower in fetuses developing postnatal renal failure. Conclusion: Fetal renal vascularity (vascularization index and vascularization and flow index) was significantly lower in fetuses that developed renal impairment.

AB - Objective: To evaluate the applicability of 3-dimensional evaluation of renal vascularization for predicting postnatal renal function in fetuses with suspected urinary obstruction. Study Design: Fetuses were evaluated by 3-dimensional power-Doppler histogram, and vascular indices were estimated. Depth between the probe and the renal cortex was also evaluated. Postnatal follow-up was obtained in all cases and the main outcome was renal impairment. Results: Twenty-three fetuses with urinary dilatation (cases) and 73 with normal renal morphology (controls) were included in the current study. Five (21.7%) cases developed renal impairment. Vascularization index and vascularization and flow index were significantly lower in fetuses that developed renal impairment compared with those with normal renal function (P =.009 and P =.036, respectively). The 3 vascular indexes correlated with depth. Percentage of depth-corrected vascularization index and vascularization flow index were lower in fetuses developing postnatal renal failure. Conclusion: Fetal renal vascularity (vascularization index and vascularization and flow index) was significantly lower in fetuses that developed renal impairment.

KW - 3-dimensional ultrasound

KW - fetus

KW - kidney

KW - prenatal diagnosis

KW - renal function

UR - http://www.scopus.com/inward/record.url?scp=81855195314&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=81855195314&partnerID=8YFLogxK

U2 - 10.1016/j.ajog.2011.06.063

DO - 10.1016/j.ajog.2011.06.063

M3 - Article

VL - 205

JO - American Journal of Obstetrics and Gynecology

JF - American Journal of Obstetrics and Gynecology

SN - 0002-9378

IS - 6

ER -