Quantitation of the in vivo kidney volume with cine computed tomography

Lilach O. Lerman, Michael D. Bentley, Malcolm R. Bell, John A. Rumberger, J. Carlos Romero

Research output: Contribution to journalArticle

50 Scopus citations

Abstract

The authors examined the utility of cine computerized tomography (CT) for noninvasive determination of whole kidney, cortical, and medullary volumes. The right kidneys of 14 anesthetized dogs were scanned after an intravenous bolus injection of iohexol, and their volumes determined after boundary identification. After the scans, the kidneys were excised at postmortem examination and their volumes determined by fluid displacement. The mean (± standard error of the mean [SEM]) postmortem and in vivo renal volumes were 66.1 ± 2.2 cc and 78.2 ± 2.4 cc, respectively (r = 0.86; P < 0.001). The difference was consistent with the blood, filtrate, and urine contents of the in vivo kidney. The in vivo cortical and medullary volumes correlated poorly with their postmortem volumes because of difficulties hi boundary definition. These results demonstrate the feasibility for fast and reliable in vivo whole kidney volume quantitation by cine CT.

Original languageEnglish (US)
Pages (from-to)1206-1211
Number of pages6
JournalInvestigative radiology
Volume25
Issue number11
DOIs
StatePublished - Nov 1990

Keywords

  • Cine CT
  • Cortical volume
  • Medullary volume
  • Random marking
  • Renal volume

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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