TY - JOUR
T1 - Quantifying viscoelasticity of gelatin phantoms by measuring impulse response using compact optical sensors [Correspondence]
AU - Qiang, Bo
AU - Greenleaf, James
AU - Zhang, Xiaoming
N1 - Funding Information:
Manuscript received january 3, 2010; accepted March 20, 2010. We acknowledge the financial support from a research career development award for non-clinician scientists to X. Zhang by Mayo clinic. We have a Us pending patent entitled “system and method for non-invasively measuring tissue viscoelasticity using surface waves.” The authors are with the department of Physiology and Biomedical Engineering, Mayo clinic college of Medicine, rochester, Mn (e-mail: zhang.xiaoming@mayo.edu). digital object Identifier 10.1109/TUFFc.2010.1600
PY - 2010/7
Y1 - 2010/7
N2 - Tissue elastography measures tissue mechanical properties, which contain important physiological information and help medical diagnosis. Instead of tracking shear wave propagation inside tissue as do magnetic resonance elastography and ultrasound based techniques, this study focuses on monitoring the propagation of surface Raleigh waves stimulated by short impulses. The method is noncontact, noninvasive, and low cost and has a potential for clinical applications. A customized device designed to measure surface wave propagation is constructed based on a laser displacement sensor (LDS). Experiments are carried out on two porcine skin gelatin phantoms of different concentrations. For each phantom, the phase velocities of specific frequencies are extracted using a cross-spectrum method and then the material elasticity and viscosity are found by fitting the phase velocities with the Voigt's model. The results suggest that measuring viscoelasticity by monitoring the response to a surface impulse is an efficient method because of the richness of frequency content of impulse responses. The results are validated with a standard continuous wave (CW) method.
AB - Tissue elastography measures tissue mechanical properties, which contain important physiological information and help medical diagnosis. Instead of tracking shear wave propagation inside tissue as do magnetic resonance elastography and ultrasound based techniques, this study focuses on monitoring the propagation of surface Raleigh waves stimulated by short impulses. The method is noncontact, noninvasive, and low cost and has a potential for clinical applications. A customized device designed to measure surface wave propagation is constructed based on a laser displacement sensor (LDS). Experiments are carried out on two porcine skin gelatin phantoms of different concentrations. For each phantom, the phase velocities of specific frequencies are extracted using a cross-spectrum method and then the material elasticity and viscosity are found by fitting the phase velocities with the Voigt's model. The results suggest that measuring viscoelasticity by monitoring the response to a surface impulse is an efficient method because of the richness of frequency content of impulse responses. The results are validated with a standard continuous wave (CW) method.
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U2 - 10.1109/TUFFC.2010.1600
DO - 10.1109/TUFFC.2010.1600
M3 - Article
C2 - 20639163
AN - SCOPUS:77954769837
SN - 0885-3010
VL - 57
SP - 1696
EP - 1700
JO - IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
JF - IEEE Transactions on Ultrasonics, Ferroelectrics, and Frequency Control
IS - 7
M1 - 5507672
ER -