Quantifying glioma cell growth and invasion in vitro

Research output: Contribution to journalArticle

30 Citations (Scopus)

Abstract

A mathematical model has been developed to describe and quantify the growth and invasion of gliomas (the most common type of primary brain tumors). The model has already been shown to agree well with in vivo imaging studies of gliomas. Here we demonstrate the model's agreement with in vitro experimental data. The analysis provided in this article demonstrates that the model agrees well with published observations of growth and invasion of gliomas cells in culture. These in vitro results support the model's utility in describing the behavior of glioma cells in experimental settings but also lends credence to the applications of the model to the in vivo setting.

Original languageEnglish (US)
Pages (from-to)638-648
Number of pages11
JournalMathematical and Computer Modelling
Volume47
Issue number5-6
DOIs
StatePublished - Mar 2008
Externally publishedYes

Fingerprint

Invasion
Cell growth
Cell
Brain Tumor
Model
Demonstrate
Tumors
Brain
Quantify
Imaging
Experimental Data
Mathematical Model
Mathematical models
Imaging techniques

Keywords

  • Brain tumor
  • Glioma
  • Invasion
  • Mathematical model

ASJC Scopus subject areas

  • Information Systems and Management
  • Control and Systems Engineering
  • Applied Mathematics
  • Computational Mathematics
  • Modeling and Simulation
  • Computer Science (miscellaneous)

Cite this

Quantifying glioma cell growth and invasion in vitro. / Swanson, Kristin.

In: Mathematical and Computer Modelling, Vol. 47, No. 5-6, 03.2008, p. 638-648.

Research output: Contribution to journalArticle

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