Quantification of pulmonary vein morphology using centerline tracking

M. E. Rettmann, M. S. Gunawan, D. R. Holmes, D. L. Packer, R. A. Robb

Research output: Chapter in Book/Report/Conference proceedingConference contribution

1 Scopus citations

Abstract

The assessment of left atrial and pulmonary vein morphology has important applications in the context of atrial fibrillation, a condition in which the atria of the heart beat rapidly and irregularly. Following ablation therapy, a treatment strategy for atrial fibrillation, reverse structural remodeling has been demonstrated with decreases in both left atrial size and pulmonary vein diameters. Most techniques for assessment of pulmonary vein morphology, however, consist of manual measurements made on cross-sectional images or volume renderings, thereby limiting the ability to fully quantify the 3D structure of the veins. In this work, we propose a method to quantify the 3D morphology of the pulmonary veins by computing the cross-sectional area along the entire extent of the vein. A centerline is tracked along the vein and oblique image slices are extracted at each point along the curve. The overall method requires only minimal manual interaction during the data pre-processing steps and is demonstrated on each of the four pulmononary veins in five subjects scanned with CT imaging prior to ablation therapy.

Original languageEnglish (US)
Title of host publication2012 9th IEEE International Symposium on Biomedical Imaging
Subtitle of host publicationFrom Nano to Macro, ISBI 2012 - Proceedings
Pages816-819
Number of pages4
DOIs
StatePublished - Aug 15 2012
Event2012 9th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2012 - Barcelona, Spain
Duration: May 2 2012May 5 2012

Publication series

NameProceedings - International Symposium on Biomedical Imaging
ISSN (Print)1945-7928
ISSN (Electronic)1945-8452

Other

Other2012 9th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2012
CountrySpain
CityBarcelona
Period5/2/125/5/12

Keywords

  • cardiac ablation therapy
  • centerline tracking
  • left atrial fibrillation
  • pulmonary veins

ASJC Scopus subject areas

  • Biomedical Engineering
  • Radiology Nuclear Medicine and imaging

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    Rettmann, M. E., Gunawan, M. S., Holmes, D. R., Packer, D. L., & Robb, R. A. (2012). Quantification of pulmonary vein morphology using centerline tracking. In 2012 9th IEEE International Symposium on Biomedical Imaging: From Nano to Macro, ISBI 2012 - Proceedings (pp. 816-819). [6235673] (Proceedings - International Symposium on Biomedical Imaging). https://doi.org/10.1109/ISBI.2012.6235673