Quality of life improvements at one, two, and five years after liver transplantation

M. F. Levy, L. Jennings, M. S. Abouljoud, D. C. Mulligan, R. M. Goldstein, B. S. Husberg, T. A. Gonwa, G. B. Klintmalm

Research output: Contribution to journalArticle

72 Citations (Scopus)

Abstract

We prospectively studied adult liver transplant (OLTX) recipients to evaluate the effect of OLTX on quality of life (QOL). Over an 8-year period, all adult patients undergoing OLTX at our institution were asked to complete a psychological questionnaire that probed broad facets of QOL. Patients seen for their 1, 2, and 5 or more-year post-OLTX visits were also asked to complete the form. Questions were then grouped by categories broadly highlighting self-image (SI), health perception (HP), ability to function (F), and ability to work (W). Questions ranged from demographic and occupational topics to symptom distress/frequency, activities of daily living, and the impact of health on daily life. Numerical scores were assigned to each question, and added to derive scores on SI, HP, and F. Higher scores reflect better QOL. Employment data (W) were also compared, though not amenable to scoring. A total of 573 forms were completed (210 protransplant, 150 at 1 year, 131 at 2 years, 79 at 5 years). All posttransplant scores were significantly higher than protransplant ones (P≤.0001, ANOVA). Scores at posttransplant time points were not significantly different from each other. Subscores of SI and HP revealed less symptom frequency and distress following OLTX (P≤.0003) continuing to beyond 5 years. Health limitations on activities decreased both at 1 year post-OLTX and again at 2 years (P≤.0001) and were sustained to beyond 5 years. Fewer people were working for pay at 1 year post-compared with pre-OLTX, but pre- OLTX levels of employment had been regained by the second year, continuing to increase to beyond 5 years. OLTX leads to improved QOL by the end of the first posttransplant year, sustained through the 5th posttransplant year and beyond. Self-image, functioning ability, and perception of health status were significantly improved. Ill health interference in daily life continues to decrease as OLTX becomes more remote. Employment suffers early after OLTX, but recovers by the second post-OLTX year and continues to increase long- term.

Original languageEnglish (US)
Pages (from-to)515-518
Number of pages4
JournalTransplantation
Volume59
Issue number4
StatePublished - 1995
Externally publishedYes

Fingerprint

Quality Improvement
Liver Transplantation
Quality of Life
Aptitude
Health
Activities of Daily Living
Health Status
Analysis of Variance
Demography
Psychology
Liver

ASJC Scopus subject areas

  • Immunology
  • Transplantation

Cite this

Levy, M. F., Jennings, L., Abouljoud, M. S., Mulligan, D. C., Goldstein, R. M., Husberg, B. S., ... Klintmalm, G. B. (1995). Quality of life improvements at one, two, and five years after liver transplantation. Transplantation, 59(4), 515-518.

Quality of life improvements at one, two, and five years after liver transplantation. / Levy, M. F.; Jennings, L.; Abouljoud, M. S.; Mulligan, D. C.; Goldstein, R. M.; Husberg, B. S.; Gonwa, T. A.; Klintmalm, G. B.

In: Transplantation, Vol. 59, No. 4, 1995, p. 515-518.

Research output: Contribution to journalArticle

Levy, MF, Jennings, L, Abouljoud, MS, Mulligan, DC, Goldstein, RM, Husberg, BS, Gonwa, TA & Klintmalm, GB 1995, 'Quality of life improvements at one, two, and five years after liver transplantation', Transplantation, vol. 59, no. 4, pp. 515-518.
Levy MF, Jennings L, Abouljoud MS, Mulligan DC, Goldstein RM, Husberg BS et al. Quality of life improvements at one, two, and five years after liver transplantation. Transplantation. 1995;59(4):515-518.
Levy, M. F. ; Jennings, L. ; Abouljoud, M. S. ; Mulligan, D. C. ; Goldstein, R. M. ; Husberg, B. S. ; Gonwa, T. A. ; Klintmalm, G. B. / Quality of life improvements at one, two, and five years after liver transplantation. In: Transplantation. 1995 ; Vol. 59, No. 4. pp. 515-518.
@article{39f9fb40484447b98bfc9bbf47b701f7,
title = "Quality of life improvements at one, two, and five years after liver transplantation",
abstract = "We prospectively studied adult liver transplant (OLTX) recipients to evaluate the effect of OLTX on quality of life (QOL). Over an 8-year period, all adult patients undergoing OLTX at our institution were asked to complete a psychological questionnaire that probed broad facets of QOL. Patients seen for their 1, 2, and 5 or more-year post-OLTX visits were also asked to complete the form. Questions were then grouped by categories broadly highlighting self-image (SI), health perception (HP), ability to function (F), and ability to work (W). Questions ranged from demographic and occupational topics to symptom distress/frequency, activities of daily living, and the impact of health on daily life. Numerical scores were assigned to each question, and added to derive scores on SI, HP, and F. Higher scores reflect better QOL. Employment data (W) were also compared, though not amenable to scoring. A total of 573 forms were completed (210 protransplant, 150 at 1 year, 131 at 2 years, 79 at 5 years). All posttransplant scores were significantly higher than protransplant ones (P≤.0001, ANOVA). Scores at posttransplant time points were not significantly different from each other. Subscores of SI and HP revealed less symptom frequency and distress following OLTX (P≤.0003) continuing to beyond 5 years. Health limitations on activities decreased both at 1 year post-OLTX and again at 2 years (P≤.0001) and were sustained to beyond 5 years. Fewer people were working for pay at 1 year post-compared with pre-OLTX, but pre- OLTX levels of employment had been regained by the second year, continuing to increase to beyond 5 years. OLTX leads to improved QOL by the end of the first posttransplant year, sustained through the 5th posttransplant year and beyond. Self-image, functioning ability, and perception of health status were significantly improved. Ill health interference in daily life continues to decrease as OLTX becomes more remote. Employment suffers early after OLTX, but recovers by the second post-OLTX year and continues to increase long- term.",
author = "Levy, {M. F.} and L. Jennings and Abouljoud, {M. S.} and Mulligan, {D. C.} and Goldstein, {R. M.} and Husberg, {B. S.} and Gonwa, {T. A.} and Klintmalm, {G. B.}",
year = "1995",
language = "English (US)",
volume = "59",
pages = "515--518",
journal = "Transplantation",
issn = "0041-1337",
publisher = "Lippincott Williams and Wilkins",
number = "4",

}

TY - JOUR

T1 - Quality of life improvements at one, two, and five years after liver transplantation

AU - Levy, M. F.

AU - Jennings, L.

AU - Abouljoud, M. S.

AU - Mulligan, D. C.

AU - Goldstein, R. M.

AU - Husberg, B. S.

AU - Gonwa, T. A.

AU - Klintmalm, G. B.

PY - 1995

Y1 - 1995

N2 - We prospectively studied adult liver transplant (OLTX) recipients to evaluate the effect of OLTX on quality of life (QOL). Over an 8-year period, all adult patients undergoing OLTX at our institution were asked to complete a psychological questionnaire that probed broad facets of QOL. Patients seen for their 1, 2, and 5 or more-year post-OLTX visits were also asked to complete the form. Questions were then grouped by categories broadly highlighting self-image (SI), health perception (HP), ability to function (F), and ability to work (W). Questions ranged from demographic and occupational topics to symptom distress/frequency, activities of daily living, and the impact of health on daily life. Numerical scores were assigned to each question, and added to derive scores on SI, HP, and F. Higher scores reflect better QOL. Employment data (W) were also compared, though not amenable to scoring. A total of 573 forms were completed (210 protransplant, 150 at 1 year, 131 at 2 years, 79 at 5 years). All posttransplant scores were significantly higher than protransplant ones (P≤.0001, ANOVA). Scores at posttransplant time points were not significantly different from each other. Subscores of SI and HP revealed less symptom frequency and distress following OLTX (P≤.0003) continuing to beyond 5 years. Health limitations on activities decreased both at 1 year post-OLTX and again at 2 years (P≤.0001) and were sustained to beyond 5 years. Fewer people were working for pay at 1 year post-compared with pre-OLTX, but pre- OLTX levels of employment had been regained by the second year, continuing to increase to beyond 5 years. OLTX leads to improved QOL by the end of the first posttransplant year, sustained through the 5th posttransplant year and beyond. Self-image, functioning ability, and perception of health status were significantly improved. Ill health interference in daily life continues to decrease as OLTX becomes more remote. Employment suffers early after OLTX, but recovers by the second post-OLTX year and continues to increase long- term.

AB - We prospectively studied adult liver transplant (OLTX) recipients to evaluate the effect of OLTX on quality of life (QOL). Over an 8-year period, all adult patients undergoing OLTX at our institution were asked to complete a psychological questionnaire that probed broad facets of QOL. Patients seen for their 1, 2, and 5 or more-year post-OLTX visits were also asked to complete the form. Questions were then grouped by categories broadly highlighting self-image (SI), health perception (HP), ability to function (F), and ability to work (W). Questions ranged from demographic and occupational topics to symptom distress/frequency, activities of daily living, and the impact of health on daily life. Numerical scores were assigned to each question, and added to derive scores on SI, HP, and F. Higher scores reflect better QOL. Employment data (W) were also compared, though not amenable to scoring. A total of 573 forms were completed (210 protransplant, 150 at 1 year, 131 at 2 years, 79 at 5 years). All posttransplant scores were significantly higher than protransplant ones (P≤.0001, ANOVA). Scores at posttransplant time points were not significantly different from each other. Subscores of SI and HP revealed less symptom frequency and distress following OLTX (P≤.0003) continuing to beyond 5 years. Health limitations on activities decreased both at 1 year post-OLTX and again at 2 years (P≤.0001) and were sustained to beyond 5 years. Fewer people were working for pay at 1 year post-compared with pre-OLTX, but pre- OLTX levels of employment had been regained by the second year, continuing to increase to beyond 5 years. OLTX leads to improved QOL by the end of the first posttransplant year, sustained through the 5th posttransplant year and beyond. Self-image, functioning ability, and perception of health status were significantly improved. Ill health interference in daily life continues to decrease as OLTX becomes more remote. Employment suffers early after OLTX, but recovers by the second post-OLTX year and continues to increase long- term.

UR - http://www.scopus.com/inward/record.url?scp=0028961540&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=0028961540&partnerID=8YFLogxK

M3 - Article

C2 - 7878756

AN - SCOPUS:0028961540

VL - 59

SP - 515

EP - 518

JO - Transplantation

JF - Transplantation

SN - 0041-1337

IS - 4

ER -