Pyrrole-based partial peptidic mimic of neurotensin (8-13): Design and synthesis

Javid H. Zaidi, Fazal Naeem, Nida Ambreen, Khalid M. Khan, Yuan-Ping Pang, Bernadette Cusack, Elliot Richelson, Awais Anwar, Wolfgang Voelter

Research output: Contribution to journalArticle

2 Citations (Scopus)

Abstract

The synthesis of pyrrole-based semipeptidic mimic of neuropeptide neurotensin (8-13) [NT(8-13)] is described. The design of this NT mimic is based on substitution of indole by a pyrrole nucleus.

Original languageEnglish (US)
Pages (from-to)21-24
Number of pages4
JournalLetters in Organic Chemistry
Volume3
Issue number1
DOIs
StatePublished - Jan 2006

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neurotensin (8-13)
Pyrroles
Neuropeptides
Substitution reactions

Keywords

  • Drug design
  • Neurotensin
  • Partial peptidic mimic
  • Synthesis

ASJC Scopus subject areas

  • Organic Chemistry
  • Biochemistry

Cite this

Pyrrole-based partial peptidic mimic of neurotensin (8-13) : Design and synthesis. / Zaidi, Javid H.; Naeem, Fazal; Ambreen, Nida; Khan, Khalid M.; Pang, Yuan-Ping; Cusack, Bernadette; Richelson, Elliot; Anwar, Awais; Voelter, Wolfgang.

In: Letters in Organic Chemistry, Vol. 3, No. 1, 01.2006, p. 21-24.

Research output: Contribution to journalArticle

Zaidi, JH, Naeem, F, Ambreen, N, Khan, KM, Pang, Y-P, Cusack, B, Richelson, E, Anwar, A & Voelter, W 2006, 'Pyrrole-based partial peptidic mimic of neurotensin (8-13): Design and synthesis', Letters in Organic Chemistry, vol. 3, no. 1, pp. 21-24. https://doi.org/10.2174/157017806774964530
Zaidi, Javid H. ; Naeem, Fazal ; Ambreen, Nida ; Khan, Khalid M. ; Pang, Yuan-Ping ; Cusack, Bernadette ; Richelson, Elliot ; Anwar, Awais ; Voelter, Wolfgang. / Pyrrole-based partial peptidic mimic of neurotensin (8-13) : Design and synthesis. In: Letters in Organic Chemistry. 2006 ; Vol. 3, No. 1. pp. 21-24.
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