Pyrrole-based partial peptidic mimic of neurotensin (8-13): Design and synthesis

Javid H. Zaidi, Fazal Naeem, Nida Ambreen, Khalid M. Khan, Yuan Ping Pang, Bernadette Cusack, Elliot Richelson, Awais Anwar, Wolfgang Voelter

Research output: Contribution to journalArticle

2 Scopus citations

Abstract

The synthesis of pyrrole-based semipeptidic mimic of neuropeptide neurotensin (8-13) [NT(8-13)] is described. The design of this NT mimic is based on substitution of indole by a pyrrole nucleus.

Original languageEnglish (US)
Pages (from-to)21-24
Number of pages4
JournalLetters in Organic Chemistry
Volume3
Issue number1
DOIs
StatePublished - Jan 1 2006

Keywords

  • Drug design
  • Neurotensin
  • Partial peptidic mimic
  • Synthesis

ASJC Scopus subject areas

  • Biochemistry
  • Organic Chemistry

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  • Cite this

    Zaidi, J. H., Naeem, F., Ambreen, N., Khan, K. M., Pang, Y. P., Cusack, B., Richelson, E., Anwar, A., & Voelter, W. (2006). Pyrrole-based partial peptidic mimic of neurotensin (8-13): Design and synthesis. Letters in Organic Chemistry, 3(1), 21-24. https://doi.org/10.2174/157017806774964530