Pulmonary venous pressure

Relationship to pulmonary artery, pulmonary wedge, and left atrial pressure in normal, lightly sedated dogs

Hari P Chaliki, David G. Hurrell, Rick A. Nishimura, Rebekah A. Reinke, Christopher P. Appleton

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Because pulmonary venous pressure has never been measured, it is unclear whether pulmonary wedge pressure measures left atrial pressure, as commonly assumed, or pressure more upstream in the pulmonary venous or capillary beds. Fluid-filled mean pulmonary artery and pulmonary wedge pressure were compared with pulmonary venous and left atrial pressure obtained with high-fidelity micromanometer catheters in eight lightly sedated dogs over a physiologic range of filling pressures. In all conditions, mean pulmonary wedge pressure was virtually identical (r = 0.99) to mean left atrial pressure (slope = 0.99; intercept = -0.46 mm Hg). At the same time, mean pulmonary venous pressure (17.1 ± 6.5 mm Hg) was intermediate between mean pulmonary artery pressure (20.2 ± 6.2 mm Hg) and mean pulmonary wedge pressure (13.3 ± 6.2 mm Hg; P < 0.0001) or mean left atrial pressure (13.4 ± 6.3 mm Hg; P < 0.0001). These relationships were maintained over normal and increased pressure ranges. As measured by conventional flow-directed pulmonary catheters, mean pulmonary wedge pressure accurately reflects left atrial pressure in lightly sedated, spontaneously breathing normal dogs.

Original languageEnglish (US)
Pages (from-to)432-438
Number of pages7
JournalCatheterization and Cardiovascular Interventions
Volume56
Issue number3
DOIs
StatePublished - 2002

Fingerprint

Pulmonary Wedge Pressure
Venous Pressure
Atrial Pressure
Pulmonary Artery
Dogs
Lung
Pressure
Catheters
Respiration

Keywords

  • Left atrial pressure
  • Pulmonary venous pressure
  • Pulmonary wedge pressure

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Radiology Nuclear Medicine and imaging

Cite this

Pulmonary venous pressure : Relationship to pulmonary artery, pulmonary wedge, and left atrial pressure in normal, lightly sedated dogs. / Chaliki, Hari P; Hurrell, David G.; Nishimura, Rick A.; Reinke, Rebekah A.; Appleton, Christopher P.

In: Catheterization and Cardiovascular Interventions, Vol. 56, No. 3, 2002, p. 432-438.

Research output: Contribution to journalArticle

Chaliki, Hari P ; Hurrell, David G. ; Nishimura, Rick A. ; Reinke, Rebekah A. ; Appleton, Christopher P. / Pulmonary venous pressure : Relationship to pulmonary artery, pulmonary wedge, and left atrial pressure in normal, lightly sedated dogs. In: Catheterization and Cardiovascular Interventions. 2002 ; Vol. 56, No. 3. pp. 432-438.
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