TY - JOUR
T1 - Pulmonary manifestations of inflammatory bowel disease
T2 - Case presentations and review
AU - Basseri, Benjamin
AU - Enayati, Pedram
AU - Marchevsky, Alberto
AU - Papadakis, Konstantinos A.
PY - 2010/10
Y1 - 2010/10
N2 - Inflammatory bowel disease (IBD) is associated with a number of extraintestinal manifestations that may involve most organ systems. Extraintestinal manifestations are more common in Crohn disease (CD) and may include rheumatologic, ocular, dermatologic, biliary and pulmonary manifestations. The most common pulmonary manifestations of IBD are drug-induced lung disease. Other manifestations include parenchymal disease, pleuritis and overlap syndromes. We present a case series of 7 patients with non-infectious pulmonary manifestations of IBD, which included cryptogenic organizing pneumonia, usual interstitial pneumonitis (UIP), Langerhan's granulomatosis, and eosinophilic pneumonia. Concurrent extraintestinal manifestations present in these patients included arthralgia, iritis, and pyoderma gangrenosum. In most patients the development of pulmonary disease parallels that of the intestinal disease activity, extraintestinal manifestations and concurrent use of 5-ASA medications.
AB - Inflammatory bowel disease (IBD) is associated with a number of extraintestinal manifestations that may involve most organ systems. Extraintestinal manifestations are more common in Crohn disease (CD) and may include rheumatologic, ocular, dermatologic, biliary and pulmonary manifestations. The most common pulmonary manifestations of IBD are drug-induced lung disease. Other manifestations include parenchymal disease, pleuritis and overlap syndromes. We present a case series of 7 patients with non-infectious pulmonary manifestations of IBD, which included cryptogenic organizing pneumonia, usual interstitial pneumonitis (UIP), Langerhan's granulomatosis, and eosinophilic pneumonia. Concurrent extraintestinal manifestations present in these patients included arthralgia, iritis, and pyoderma gangrenosum. In most patients the development of pulmonary disease parallels that of the intestinal disease activity, extraintestinal manifestations and concurrent use of 5-ASA medications.
KW - 5-ASA
KW - Crohn's disease
KW - Inflammatory bowel disease (IBD)
KW - Pulmonary manifestations
KW - Ulcerative colitis
UR - http://www.scopus.com/inward/record.url?scp=77957313219&partnerID=8YFLogxK
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U2 - 10.1016/j.crohns.2010.03.008
DO - 10.1016/j.crohns.2010.03.008
M3 - Article
C2 - 21122534
AN - SCOPUS:77957313219
SN - 1873-9946
VL - 4
SP - 390
EP - 397
JO - Journal of Crohn's and Colitis
JF - Journal of Crohn's and Colitis
IS - 4
ER -