Pulmonary inflammatory myofibroblastic tumor associated with histoplasmosis

Stephen D. Cassivi, Mark Wylam

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

Inflammatory myofibroblastic tumors of the lung in children are a non-neoplastic process characterized by an unregulated proliferation of inflammatory cells. The etiology of these 'tumors' is not certain and often difficult to ascertain. The current understanding of the pathophysiology of this lesion is based on an abnormal response by the myofibroblast to tissue injury. The vigorous immunologic response observed is commonly ascribed to a viral or foreign antigen-antibody interaction. We describe the case of an 8-year-old boy with inflammatory myofibroblastic tumor of the lung clearly associated with newly acquired infection due to histoplasma capsulatum and we review the current pertinent literature.

Original languageEnglish (US)
Pages (from-to)514-516
Number of pages3
JournalInteractive Cardiovascular and Thoracic Surgery
Volume5
Issue number4
DOIs
StatePublished - Aug 1 2006

Fingerprint

Histoplasmosis
Lung
Histoplasma
Neoplasms
Myofibroblasts
Cell Proliferation
Antigens
Antibodies
Wounds and Injuries
Infection

Keywords

  • Histoplasmosis
  • Myofibroblastic tumor
  • Pseudotumor

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Pulmonary and Respiratory Medicine
  • Surgery

Cite this

Pulmonary inflammatory myofibroblastic tumor associated with histoplasmosis. / Cassivi, Stephen D.; Wylam, Mark.

In: Interactive Cardiovascular and Thoracic Surgery, Vol. 5, No. 4, 01.08.2006, p. 514-516.

Research output: Contribution to journalArticle

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