Pulmonary Infiltrates and Eosinophilia Associated With Sulfasalazine

KENNETH K. WANG, BRAD A. BOWYER, C. RICHARD FLEMING, KENNETH W. SCHROEDER

Research output: Contribution to journalArticle

47 Scopus citations

Abstract

Asymptomatic pulmonary infiltrates and eosinophilia developed in a patient with chronic ulcerative colitis 1 month after therapy with sulfasalazine had been instituted. The abnormalities resolved completely after use of the drug was discontinued. The sulfapyridine component of the sulfasalazine was the likely causative agent because 41 years earlier, the patient had experienced fever, myalgias, and eosinophilia after taking a sulfonamide. Ten previous cases of sulfasalazine pulmonary toxicity, including one fatality, have been reported.

Original languageEnglish (US)
Pages (from-to)343-346
Number of pages4
JournalMayo Clinic proceedings
Volume59
Issue number5
DOIs
StatePublished - Jan 1 1984

ASJC Scopus subject areas

  • Medicine(all)

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