Pulmonary alveolar proteinosis

David Levin, Thomas Hartman

Research output: Chapter in Book/Report/Conference proceedingChapter


Imaging description The classic appearance of pulmonary alveolar proteinosis is symmetric, predominately perihilar, ground-glass opacity with intralobular linear opacities and interlobular septal thickening (“crazy-paving” pattern) [1–3] (Figures 19.1–19.4). There is often geographic sparing of secondary lobules and periphery of the lung. Consolidation can be seen in advanced cases. Importance Pulmonary alveolar proteinosis is one of several conditions associated with a crazy-paving pattern on high-resolution CT. Knowledge of the different causes of this pattern can aid in preventing diagnostic errors [3].

Original languageEnglish (US)
Title of host publicationPearls and Pitfalls in Thoracic Imaging
Subtitle of host publicationVariants and Other Difficult Diagnoses
PublisherCambridge University Press
Number of pages2
ISBN (Electronic)9780511977701
ISBN (Print)9780521119078
StatePublished - Jan 1 2011


ASJC Scopus subject areas

  • Medicine(all)

Cite this

Levin, D., & Hartman, T. (2011). Pulmonary alveolar proteinosis. In Pearls and Pitfalls in Thoracic Imaging: Variants and Other Difficult Diagnoses (Vol. 9780521119078, pp. 50-51). Cambridge University Press. https://doi.org/10.1017/CBO9780511977701.020