Psychological distress in Rome III functional dyspepsia patients presenting for testing of gastric emptying

J. K. Dibaise, R. S. Islam, Amylou Dueck, M. C. Roarke, M. D. Crowell

Research output: Contribution to journalArticle

11 Citations (Scopus)

Abstract

Background: There have been conflicting results from studies that have evaluated psychological disturbances in functional dyspepsia (FD). We conducted a comprehensive survey of psychological measures in patients undergoing gastric emptying testing (GET) in order to determine the relationship among psychological distress, gastric emptying, and dyspeptic symptoms. Methods: Consecutive patients referred for GET were prospectively enrolled. Details regarding patient characteristics, health care utilization, dyspeptic symptoms, quality of life, and psychological dysfunction were obtained. Depression, anxiety, somatization, stress, positive and negative affect, and alexithymia were queried using validated questionnaires. We compared those dyspeptic patients who met Rome III criteria for FD to those who did not meet these criteria. Key Results: Two hundred and nine patients (160 female; mean age 46.6 years ± 17.3 years) participated. Around 151 patients (72%) met Rome III criteria for FD. In the entire group, a high level of depression, anxiety, somatization, and perceived stress was present compared to population norms. Health care seeking behavior and symptom severity were greater in those with FD and quality of life was lower compared to non-FD. Gastric emptying did not differentiate the two groups and similar degrees of psychological distress were present whether emptying was delayed or normal. Conclusions & Inferences: In patients referred for GET, substantial psychological distress is present. The degree of distress was similar regardless of whether the patient met Rome III FD criteria or not. Further evaluation of psychological dysfunction in FD patients may lead to improved diagnosis and determination of the most appropriate treatment.

Original languageEnglish (US)
Pages (from-to)196-205
Number of pages10
JournalNeurogastroenterology and Motility
Volume28
Issue number2
DOIs
StatePublished - Feb 1 2016

Fingerprint

Dyspepsia
Gastric Emptying
Psychology
Patient Acceptance of Health Care
Anxiety
Quality of Life
Depression
Affective Symptoms

Keywords

  • Alexithymia
  • Anxiety
  • Depression
  • Functional dyspepsia
  • Gastroparesis
  • Positive/negative affect
  • Somatization
  • Stress

ASJC Scopus subject areas

  • Endocrine and Autonomic Systems
  • Gastroenterology
  • Physiology

Cite this

Psychological distress in Rome III functional dyspepsia patients presenting for testing of gastric emptying. / Dibaise, J. K.; Islam, R. S.; Dueck, Amylou; Roarke, M. C.; Crowell, M. D.

In: Neurogastroenterology and Motility, Vol. 28, No. 2, 01.02.2016, p. 196-205.

Research output: Contribution to journalArticle

Dibaise, J. K. ; Islam, R. S. ; Dueck, Amylou ; Roarke, M. C. ; Crowell, M. D. / Psychological distress in Rome III functional dyspepsia patients presenting for testing of gastric emptying. In: Neurogastroenterology and Motility. 2016 ; Vol. 28, No. 2. pp. 196-205.
@article{6b1d11689f744777babd962f412c4364,
title = "Psychological distress in Rome III functional dyspepsia patients presenting for testing of gastric emptying",
abstract = "Background: There have been conflicting results from studies that have evaluated psychological disturbances in functional dyspepsia (FD). We conducted a comprehensive survey of psychological measures in patients undergoing gastric emptying testing (GET) in order to determine the relationship among psychological distress, gastric emptying, and dyspeptic symptoms. Methods: Consecutive patients referred for GET were prospectively enrolled. Details regarding patient characteristics, health care utilization, dyspeptic symptoms, quality of life, and psychological dysfunction were obtained. Depression, anxiety, somatization, stress, positive and negative affect, and alexithymia were queried using validated questionnaires. We compared those dyspeptic patients who met Rome III criteria for FD to those who did not meet these criteria. Key Results: Two hundred and nine patients (160 female; mean age 46.6 years ± 17.3 years) participated. Around 151 patients (72{\%}) met Rome III criteria for FD. In the entire group, a high level of depression, anxiety, somatization, and perceived stress was present compared to population norms. Health care seeking behavior and symptom severity were greater in those with FD and quality of life was lower compared to non-FD. Gastric emptying did not differentiate the two groups and similar degrees of psychological distress were present whether emptying was delayed or normal. Conclusions & Inferences: In patients referred for GET, substantial psychological distress is present. The degree of distress was similar regardless of whether the patient met Rome III FD criteria or not. Further evaluation of psychological dysfunction in FD patients may lead to improved diagnosis and determination of the most appropriate treatment.",
keywords = "Alexithymia, Anxiety, Depression, Functional dyspepsia, Gastroparesis, Positive/negative affect, Somatization, Stress",
author = "Dibaise, {J. K.} and Islam, {R. S.} and Amylou Dueck and Roarke, {M. C.} and Crowell, {M. D.}",
year = "2016",
month = "2",
day = "1",
doi = "10.1111/nmo.12709",
language = "English (US)",
volume = "28",
pages = "196--205",
journal = "Neurogastroenterology and Motility",
issn = "1350-1925",
publisher = "Wiley-Blackwell",
number = "2",

}

TY - JOUR

T1 - Psychological distress in Rome III functional dyspepsia patients presenting for testing of gastric emptying

AU - Dibaise, J. K.

AU - Islam, R. S.

AU - Dueck, Amylou

AU - Roarke, M. C.

AU - Crowell, M. D.

PY - 2016/2/1

Y1 - 2016/2/1

N2 - Background: There have been conflicting results from studies that have evaluated psychological disturbances in functional dyspepsia (FD). We conducted a comprehensive survey of psychological measures in patients undergoing gastric emptying testing (GET) in order to determine the relationship among psychological distress, gastric emptying, and dyspeptic symptoms. Methods: Consecutive patients referred for GET were prospectively enrolled. Details regarding patient characteristics, health care utilization, dyspeptic symptoms, quality of life, and psychological dysfunction were obtained. Depression, anxiety, somatization, stress, positive and negative affect, and alexithymia were queried using validated questionnaires. We compared those dyspeptic patients who met Rome III criteria for FD to those who did not meet these criteria. Key Results: Two hundred and nine patients (160 female; mean age 46.6 years ± 17.3 years) participated. Around 151 patients (72%) met Rome III criteria for FD. In the entire group, a high level of depression, anxiety, somatization, and perceived stress was present compared to population norms. Health care seeking behavior and symptom severity were greater in those with FD and quality of life was lower compared to non-FD. Gastric emptying did not differentiate the two groups and similar degrees of psychological distress were present whether emptying was delayed or normal. Conclusions & Inferences: In patients referred for GET, substantial psychological distress is present. The degree of distress was similar regardless of whether the patient met Rome III FD criteria or not. Further evaluation of psychological dysfunction in FD patients may lead to improved diagnosis and determination of the most appropriate treatment.

AB - Background: There have been conflicting results from studies that have evaluated psychological disturbances in functional dyspepsia (FD). We conducted a comprehensive survey of psychological measures in patients undergoing gastric emptying testing (GET) in order to determine the relationship among psychological distress, gastric emptying, and dyspeptic symptoms. Methods: Consecutive patients referred for GET were prospectively enrolled. Details regarding patient characteristics, health care utilization, dyspeptic symptoms, quality of life, and psychological dysfunction were obtained. Depression, anxiety, somatization, stress, positive and negative affect, and alexithymia were queried using validated questionnaires. We compared those dyspeptic patients who met Rome III criteria for FD to those who did not meet these criteria. Key Results: Two hundred and nine patients (160 female; mean age 46.6 years ± 17.3 years) participated. Around 151 patients (72%) met Rome III criteria for FD. In the entire group, a high level of depression, anxiety, somatization, and perceived stress was present compared to population norms. Health care seeking behavior and symptom severity were greater in those with FD and quality of life was lower compared to non-FD. Gastric emptying did not differentiate the two groups and similar degrees of psychological distress were present whether emptying was delayed or normal. Conclusions & Inferences: In patients referred for GET, substantial psychological distress is present. The degree of distress was similar regardless of whether the patient met Rome III FD criteria or not. Further evaluation of psychological dysfunction in FD patients may lead to improved diagnosis and determination of the most appropriate treatment.

KW - Alexithymia

KW - Anxiety

KW - Depression

KW - Functional dyspepsia

KW - Gastroparesis

KW - Positive/negative affect

KW - Somatization

KW - Stress

UR - http://www.scopus.com/inward/record.url?scp=84956586440&partnerID=8YFLogxK

UR - http://www.scopus.com/inward/citedby.url?scp=84956586440&partnerID=8YFLogxK

U2 - 10.1111/nmo.12709

DO - 10.1111/nmo.12709

M3 - Article

C2 - 26511077

AN - SCOPUS:84956586440

VL - 28

SP - 196

EP - 205

JO - Neurogastroenterology and Motility

JF - Neurogastroenterology and Motility

SN - 1350-1925

IS - 2

ER -