Psychoemotional and quality of life response to mitral operations in patients with mitral regurgitation: A prospective study

Tali Bayer-Topilsky, Rakesh M. Suri, Yan Topilsky, Yariv N. Marmor, Max R. Trenerry, Ryan M. Antiel, Douglas W. Mahoney, Hartzell V Schaff, Maurice E Sarano

Research output: Contribution to journalArticle

7 Citations (Scopus)

Abstract

Background Severe mitral regurgitation (MR) is associated with frequent alteration of psychoemotional status (PES), with anxiety and stress symptoms related to health-related quality of life (HR-QOL). Yet, it is unknown whether surgical correction of MR leads to improvement or deterioration in PES and HR-QOL. Methods We prospectively performed comprehensive MR assessment and administered questionnaires assessing PES and HR-QOL in 131 patients (aged 60 years; 75% men) before and 6 months after operation for organic MR and compared them to 62 patients who did not undergo operation for mitral disease and 36 normal controls of similar age assessed with the same methods. Results Baseline PES was poorer preoperatively in patients undergoing mitral operation compared with patients who did not undergo mitral operation and normal controls (anxiety and posttraumatic stress [PTS]; both p < 0.01) with poorer physical HR-QOL (p < 0.01). Six months later, all these psychoemotional variables improved (all p a 0.02) in the patients who underwent mitral operation, whereas no change was observed in the other 2 groups (all p > 0.1). Improvement after mitral repair resulted in postoperative normalization of emotional and physical well-being, with similar scores among all groups (all p ≥ 0.4). At 6-month follow-up, no difference in improvement in PES and HR-QOL was noted according to the surgical approach (robotic versus sternotomy, all p < 0.2). Conclusions Patients with severe organic MR present with frequent psychoemotional alterations and HR-QOL deterioration, in contrast to patients who do not undergo mitral operation and normal controls. After mitral operation, notable improvement results in normalization of emotional and physical well-being. Quantification of emotional and physical well-being provides important outcome measures in patients with organic MR and uncovers important benefits provided by surgical correction of MR.

Original languageEnglish (US)
Pages (from-to)847-854
Number of pages8
JournalAnnals of Thoracic Surgery
Volume99
Issue number3
DOIs
StatePublished - Mar 1 2015

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Mitral Valve Insufficiency
Quality of Life
Prospective Studies
Anxiety
Sternotomy
Robotics
Outcome Assessment (Health Care)

ASJC Scopus subject areas

  • Cardiology and Cardiovascular Medicine
  • Surgery
  • Pulmonary and Respiratory Medicine

Cite this

Psychoemotional and quality of life response to mitral operations in patients with mitral regurgitation : A prospective study. / Bayer-Topilsky, Tali; Suri, Rakesh M.; Topilsky, Yan; Marmor, Yariv N.; Trenerry, Max R.; Antiel, Ryan M.; Mahoney, Douglas W.; Schaff, Hartzell V; Sarano, Maurice E.

In: Annals of Thoracic Surgery, Vol. 99, No. 3, 01.03.2015, p. 847-854.

Research output: Contribution to journalArticle

Bayer-Topilsky, Tali ; Suri, Rakesh M. ; Topilsky, Yan ; Marmor, Yariv N. ; Trenerry, Max R. ; Antiel, Ryan M. ; Mahoney, Douglas W. ; Schaff, Hartzell V ; Sarano, Maurice E. / Psychoemotional and quality of life response to mitral operations in patients with mitral regurgitation : A prospective study. In: Annals of Thoracic Surgery. 2015 ; Vol. 99, No. 3. pp. 847-854.
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title = "Psychoemotional and quality of life response to mitral operations in patients with mitral regurgitation: A prospective study",
abstract = "Background Severe mitral regurgitation (MR) is associated with frequent alteration of psychoemotional status (PES), with anxiety and stress symptoms related to health-related quality of life (HR-QOL). Yet, it is unknown whether surgical correction of MR leads to improvement or deterioration in PES and HR-QOL. Methods We prospectively performed comprehensive MR assessment and administered questionnaires assessing PES and HR-QOL in 131 patients (aged 60 years; 75{\%} men) before and 6 months after operation for organic MR and compared them to 62 patients who did not undergo operation for mitral disease and 36 normal controls of similar age assessed with the same methods. Results Baseline PES was poorer preoperatively in patients undergoing mitral operation compared with patients who did not undergo mitral operation and normal controls (anxiety and posttraumatic stress [PTS]; both p < 0.01) with poorer physical HR-QOL (p < 0.01). Six months later, all these psychoemotional variables improved (all p a 0.02) in the patients who underwent mitral operation, whereas no change was observed in the other 2 groups (all p > 0.1). Improvement after mitral repair resulted in postoperative normalization of emotional and physical well-being, with similar scores among all groups (all p {\^a}‰¥ 0.4). At 6-month follow-up, no difference in improvement in PES and HR-QOL was noted according to the surgical approach (robotic versus sternotomy, all p < 0.2). Conclusions Patients with severe organic MR present with frequent psychoemotional alterations and HR-QOL deterioration, in contrast to patients who do not undergo mitral operation and normal controls. After mitral operation, notable improvement results in normalization of emotional and physical well-being. Quantification of emotional and physical well-being provides important outcome measures in patients with organic MR and uncovers important benefits provided by surgical correction of MR.",
author = "Tali Bayer-Topilsky and Suri, {Rakesh M.} and Yan Topilsky and Marmor, {Yariv N.} and Trenerry, {Max R.} and Antiel, {Ryan M.} and Mahoney, {Douglas W.} and Schaff, {Hartzell V} and Sarano, {Maurice E}",
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T1 - Psychoemotional and quality of life response to mitral operations in patients with mitral regurgitation

T2 - A prospective study

AU - Bayer-Topilsky, Tali

AU - Suri, Rakesh M.

AU - Topilsky, Yan

AU - Marmor, Yariv N.

AU - Trenerry, Max R.

AU - Antiel, Ryan M.

AU - Mahoney, Douglas W.

AU - Schaff, Hartzell V

AU - Sarano, Maurice E

PY - 2015/3/1

Y1 - 2015/3/1

N2 - Background Severe mitral regurgitation (MR) is associated with frequent alteration of psychoemotional status (PES), with anxiety and stress symptoms related to health-related quality of life (HR-QOL). Yet, it is unknown whether surgical correction of MR leads to improvement or deterioration in PES and HR-QOL. Methods We prospectively performed comprehensive MR assessment and administered questionnaires assessing PES and HR-QOL in 131 patients (aged 60 years; 75% men) before and 6 months after operation for organic MR and compared them to 62 patients who did not undergo operation for mitral disease and 36 normal controls of similar age assessed with the same methods. Results Baseline PES was poorer preoperatively in patients undergoing mitral operation compared with patients who did not undergo mitral operation and normal controls (anxiety and posttraumatic stress [PTS]; both p < 0.01) with poorer physical HR-QOL (p < 0.01). Six months later, all these psychoemotional variables improved (all p a 0.02) in the patients who underwent mitral operation, whereas no change was observed in the other 2 groups (all p > 0.1). Improvement after mitral repair resulted in postoperative normalization of emotional and physical well-being, with similar scores among all groups (all p ≥ 0.4). At 6-month follow-up, no difference in improvement in PES and HR-QOL was noted according to the surgical approach (robotic versus sternotomy, all p < 0.2). Conclusions Patients with severe organic MR present with frequent psychoemotional alterations and HR-QOL deterioration, in contrast to patients who do not undergo mitral operation and normal controls. After mitral operation, notable improvement results in normalization of emotional and physical well-being. Quantification of emotional and physical well-being provides important outcome measures in patients with organic MR and uncovers important benefits provided by surgical correction of MR.

AB - Background Severe mitral regurgitation (MR) is associated with frequent alteration of psychoemotional status (PES), with anxiety and stress symptoms related to health-related quality of life (HR-QOL). Yet, it is unknown whether surgical correction of MR leads to improvement or deterioration in PES and HR-QOL. Methods We prospectively performed comprehensive MR assessment and administered questionnaires assessing PES and HR-QOL in 131 patients (aged 60 years; 75% men) before and 6 months after operation for organic MR and compared them to 62 patients who did not undergo operation for mitral disease and 36 normal controls of similar age assessed with the same methods. Results Baseline PES was poorer preoperatively in patients undergoing mitral operation compared with patients who did not undergo mitral operation and normal controls (anxiety and posttraumatic stress [PTS]; both p < 0.01) with poorer physical HR-QOL (p < 0.01). Six months later, all these psychoemotional variables improved (all p a 0.02) in the patients who underwent mitral operation, whereas no change was observed in the other 2 groups (all p > 0.1). Improvement after mitral repair resulted in postoperative normalization of emotional and physical well-being, with similar scores among all groups (all p ≥ 0.4). At 6-month follow-up, no difference in improvement in PES and HR-QOL was noted according to the surgical approach (robotic versus sternotomy, all p < 0.2). Conclusions Patients with severe organic MR present with frequent psychoemotional alterations and HR-QOL deterioration, in contrast to patients who do not undergo mitral operation and normal controls. After mitral operation, notable improvement results in normalization of emotional and physical well-being. Quantification of emotional and physical well-being provides important outcome measures in patients with organic MR and uncovers important benefits provided by surgical correction of MR.

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