TY - JOUR
T1 - Psychoemotional and quality of life response to mitral operations in patients with mitral regurgitation
T2 - A prospective study
AU - Bayer-Topilsky, Tali
AU - Suri, Rakesh M.
AU - Topilsky, Yan
AU - Marmor, Yariv N.
AU - Trenerry, Max R.
AU - Antiel, Ryan M.
AU - Mahoney, Douglas W.
AU - Schaff, Hartzell V.
AU - Enriquez-Sarano, Maurice
N1 - Publisher Copyright:
© 2015 The Society of Thoracic Surgeons.
PY - 2015/3/1
Y1 - 2015/3/1
N2 - Background Severe mitral regurgitation (MR) is associated with frequent alteration of psychoemotional status (PES), with anxiety and stress symptoms related to health-related quality of life (HR-QOL). Yet, it is unknown whether surgical correction of MR leads to improvement or deterioration in PES and HR-QOL. Methods We prospectively performed comprehensive MR assessment and administered questionnaires assessing PES and HR-QOL in 131 patients (aged 60 years; 75% men) before and 6 months after operation for organic MR and compared them to 62 patients who did not undergo operation for mitral disease and 36 normal controls of similar age assessed with the same methods. Results Baseline PES was poorer preoperatively in patients undergoing mitral operation compared with patients who did not undergo mitral operation and normal controls (anxiety and posttraumatic stress [PTS]; both p < 0.01) with poorer physical HR-QOL (p < 0.01). Six months later, all these psychoemotional variables improved (all p a 0.02) in the patients who underwent mitral operation, whereas no change was observed in the other 2 groups (all p > 0.1). Improvement after mitral repair resulted in postoperative normalization of emotional and physical well-being, with similar scores among all groups (all p ≥ 0.4). At 6-month follow-up, no difference in improvement in PES and HR-QOL was noted according to the surgical approach (robotic versus sternotomy, all p < 0.2). Conclusions Patients with severe organic MR present with frequent psychoemotional alterations and HR-QOL deterioration, in contrast to patients who do not undergo mitral operation and normal controls. After mitral operation, notable improvement results in normalization of emotional and physical well-being. Quantification of emotional and physical well-being provides important outcome measures in patients with organic MR and uncovers important benefits provided by surgical correction of MR.
AB - Background Severe mitral regurgitation (MR) is associated with frequent alteration of psychoemotional status (PES), with anxiety and stress symptoms related to health-related quality of life (HR-QOL). Yet, it is unknown whether surgical correction of MR leads to improvement or deterioration in PES and HR-QOL. Methods We prospectively performed comprehensive MR assessment and administered questionnaires assessing PES and HR-QOL in 131 patients (aged 60 years; 75% men) before and 6 months after operation for organic MR and compared them to 62 patients who did not undergo operation for mitral disease and 36 normal controls of similar age assessed with the same methods. Results Baseline PES was poorer preoperatively in patients undergoing mitral operation compared with patients who did not undergo mitral operation and normal controls (anxiety and posttraumatic stress [PTS]; both p < 0.01) with poorer physical HR-QOL (p < 0.01). Six months later, all these psychoemotional variables improved (all p a 0.02) in the patients who underwent mitral operation, whereas no change was observed in the other 2 groups (all p > 0.1). Improvement after mitral repair resulted in postoperative normalization of emotional and physical well-being, with similar scores among all groups (all p ≥ 0.4). At 6-month follow-up, no difference in improvement in PES and HR-QOL was noted according to the surgical approach (robotic versus sternotomy, all p < 0.2). Conclusions Patients with severe organic MR present with frequent psychoemotional alterations and HR-QOL deterioration, in contrast to patients who do not undergo mitral operation and normal controls. After mitral operation, notable improvement results in normalization of emotional and physical well-being. Quantification of emotional and physical well-being provides important outcome measures in patients with organic MR and uncovers important benefits provided by surgical correction of MR.
UR - http://www.scopus.com/inward/record.url?scp=84924557050&partnerID=8YFLogxK
UR - http://www.scopus.com/inward/citedby.url?scp=84924557050&partnerID=8YFLogxK
U2 - 10.1016/j.athoracsur.2014.10.030
DO - 10.1016/j.athoracsur.2014.10.030
M3 - Article
C2 - 25620595
AN - SCOPUS:84924557050
SN - 0003-4975
VL - 99
SP - 847
EP - 854
JO - Annals of Thoracic Surgery
JF - Annals of Thoracic Surgery
IS - 3
ER -