Proteomics of human pancreatic juice

Mads Gronborg, Anirban Maitra, Akhilesh Pandey

Research output: Chapter in Book/Report/Conference proceedingChapter

Abstract

Pancreatic juice has recently been characterized in detail using proteomic methods. The cataloging of proteins from healthy individuals and those diagnosed with pancreatic cancer has revealed the presence of a number of proteins in pancreatic juice that could serve as potential biomarkers for cancer. Because obtaining pancreatic juice is not trivial, it is possible that these biomarkers can be detected in serum using more sensitive methods like ELISA. Here, we discuss the protein constituents of pancreatic juice with special reference to cancer biomarkers.

Original languageEnglish (US)
Title of host publicationProteomics of Human Body Fluids
Subtitle of host publicationPrinciples, Methods, and Applications
PublisherHumana Press Inc.
Pages377-397
Number of pages21
ISBN (Electronic)9781597454322
ISBN (Print)9781588296573
DOIs
StatePublished - Jan 1 2007

Keywords

  • LC-MS/MS
  • Pancreatic juice
  • biomarker discovery
  • mass spectrometry
  • quantitative proteomics

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

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  • Cite this

    Gronborg, M., Maitra, A., & Pandey, A. (2007). Proteomics of human pancreatic juice. In Proteomics of Human Body Fluids: Principles, Methods, and Applications (pp. 377-397). Humana Press Inc.. https://doi.org/10.1007/978-1-59745-432-2_17