Proteomics of human bile

Troels Zakarias Kristiansen, Anirban Maitra, Akhilesh Pandey

Research output: Chapter in Book/Report/Conference proceedingChapter

7 Scopus citations

Abstract

Bile is an important body fluid with crucial functions ranging from fat absorption to excretion of metabolic breakdown products. Although the chemical composition of human bile is well understood, its protein constituents are beginning to be unravelled only recently. Here, we provide an overview of the proteomics of human bile, both in health and in diseases such as cholangiocarcinoma. A comprehensive catalog of proteins in the bile should facilitate better understanding of its role in physiology and the development and validation of biomarkers for hepatobiliary disorders.

Original languageEnglish (US)
Title of host publicationProteomics of Human Body Fluids
Subtitle of host publicationPrinciples, Methods, and Applications
PublisherHumana Press Inc.
Pages399-414
Number of pages16
ISBN (Electronic)9781597454322
ISBN (Print)9781588296573
DOIs
StatePublished - Jan 1 2007

Keywords

  • Bile
  • LC-MS/MS
  • biomarker discovery
  • hepatobiliary cancer
  • mass spectrometry
  • proteomics

ASJC Scopus subject areas

  • Biochemistry, Genetics and Molecular Biology(all)

Fingerprint Dive into the research topics of 'Proteomics of human bile'. Together they form a unique fingerprint.

  • Cite this

    Kristiansen, T. Z., Maitra, A., & Pandey, A. (2007). Proteomics of human bile. In Proteomics of Human Body Fluids: Principles, Methods, and Applications (pp. 399-414). Humana Press Inc.. https://doi.org/10.1007/978-1-59745-432-2_18