TY - JOUR
T1 - Prosthetic joint infections
AU - Sia, Irene G.
AU - Berbari, Elie F.
AU - Karchmer, Adolf W.
PY - 2005/12
Y1 - 2005/12
N2 - Success in the treatment of infected orthopedic prosthesis requires the best surgical approach in combination with prolonged optimum targeted antimicrobial therapy. In choosing the surgical option, one must consider the type of infection, condition of the bone stock and soft tissue, the virulence and antimicrobial susceptibility of the pathogen, the general health and projected longevity of the patient, and the experience of the surgeon. If surgery is not possible, an alternative is long-term oral antimicrobial suppression to maintain a functioning prosthesis. Treatment must be individualized for a specific infection in a specific patient.
AB - Success in the treatment of infected orthopedic prosthesis requires the best surgical approach in combination with prolonged optimum targeted antimicrobial therapy. In choosing the surgical option, one must consider the type of infection, condition of the bone stock and soft tissue, the virulence and antimicrobial susceptibility of the pathogen, the general health and projected longevity of the patient, and the experience of the surgeon. If surgery is not possible, an alternative is long-term oral antimicrobial suppression to maintain a functioning prosthesis. Treatment must be individualized for a specific infection in a specific patient.
UR - http://www.scopus.com/inward/record.url?scp=27744460481&partnerID=8YFLogxK
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U2 - 10.1016/j.idc.2005.07.010
DO - 10.1016/j.idc.2005.07.010
M3 - Review article
C2 - 16297738
AN - SCOPUS:27744460481
SN - 0891-5520
VL - 19
SP - 885
EP - 914
JO - Infectious Disease Clinics of North America
JF - Infectious Disease Clinics of North America
IS - 4
ER -