TY - JOUR
T1 - Prostate cancer disparities in Black men of African descent
T2 - A comparative literature review of prostate cancer burden among Black men in the United States, Caribbean, United Kingdom, and West Africa
AU - Odedina, Folakemi T.
AU - Akinremi, Titilola O.
AU - Chinegwundoh, Frank
AU - Roberts, Robin
AU - Yu, Daohai
AU - Reams, R. Renee
AU - Freedman, Matthew L.
AU - Rivers, Brian
AU - Green, B. Lee
AU - Kumar, Nagi
N1 - Funding Information:
The research initiative for this manuscript was supported by the Department of Defense Prostate Cancer Research Program W81XWH-04-1-0326.
Funding Information:
<supplement> <title> <p>Second Annual International African-Caribbean Cancer Consortium Conference</p> </title> <editor>Camille Ragin and Emanuela Taioli</editor> <sponsor> <note>Publication supported in part by the University Of Pittsburgh Graduate School Of Public Health, the University of Pittsburgh Cancer Institute, and by the National Institute of Health, grant number R13CA130596A.</note> </sponsor> <note>Proceedings</note> <url>http://www.biomedcentral.com/content/pdf/1750-9378-4-S1-info.pdf</url> </supplement>
PY - 2009
Y1 - 2009
N2 - Background. African American men have the highest prostate cancer morbidity and mortality rates than any other racial or ethnic group in the US. Although the overall incidence of and mortality from prostate cancer has been declining in White men since 1991, the decline in African American men lags behind White men. Of particular concern is the growing literature on the disproportionate burden of prostate cancer among other Black men of West African ancestry in the Caribbean Islands, United Kingdom and West Africa. This higher incidence of prostate cancer observed in populations of African descent may be attributed to the fact that these populations share ancestral genetic factors. To better understand the burden of prostate cancer among men of West African Ancestry, we conducted a review of the literature on prostate cancer incidence, prevalence, and mortality in the countries connected by the Transatlantic Slave Trade. Results. Several published studies indicate high prostate cancer burden in Nigeria and Ghana. There was no published literature for the countries Benin, Gambia and Senegal that met our review criteria. Prostate cancer morbidity and/or mortality data from the Caribbean Islands and the United Kingdom also provided comparable or worse prostate cancer burden to that of US Blacks. Conclusion. The growing literature on the disproportionate burden of prostate cancer among other Black men of West African ancestry follows the path of the Transatlantic Slave Trade. To better understand and address the global prostate cancer disparities seen in Black men of West African ancestry, future studies should explore the genetic and environmental risk factors for prostate cancer among this group.
AB - Background. African American men have the highest prostate cancer morbidity and mortality rates than any other racial or ethnic group in the US. Although the overall incidence of and mortality from prostate cancer has been declining in White men since 1991, the decline in African American men lags behind White men. Of particular concern is the growing literature on the disproportionate burden of prostate cancer among other Black men of West African ancestry in the Caribbean Islands, United Kingdom and West Africa. This higher incidence of prostate cancer observed in populations of African descent may be attributed to the fact that these populations share ancestral genetic factors. To better understand the burden of prostate cancer among men of West African Ancestry, we conducted a review of the literature on prostate cancer incidence, prevalence, and mortality in the countries connected by the Transatlantic Slave Trade. Results. Several published studies indicate high prostate cancer burden in Nigeria and Ghana. There was no published literature for the countries Benin, Gambia and Senegal that met our review criteria. Prostate cancer morbidity and/or mortality data from the Caribbean Islands and the United Kingdom also provided comparable or worse prostate cancer burden to that of US Blacks. Conclusion. The growing literature on the disproportionate burden of prostate cancer among other Black men of West African ancestry follows the path of the Transatlantic Slave Trade. To better understand and address the global prostate cancer disparities seen in Black men of West African ancestry, future studies should explore the genetic and environmental risk factors for prostate cancer among this group.
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U2 - 10.1186/1750-9378-4-S1-S2
DO - 10.1186/1750-9378-4-S1-S2
M3 - Article
AN - SCOPUS:60349091551
SN - 1750-9378
VL - 4
JO - Infectious Agents and Cancer
JF - Infectious Agents and Cancer
IS - SUPPL. 1
M1 - S2
ER -