Prostaglandin release following Nd:YAG iridotomy in rabbits

R. Gailitis; G. A. Peyman; J. Pulido; M. D. Mitchell; R. M. Weinreb

Prostaglandin release following Nd:YAG iridotomy in rabbits

R. Gailitis, G. A. Peyman, J. Pulido, M. D. Mitchell, R. M. Weinreb

Ophthalmology

Research output: Contribution to journal › Article › peer-review

15 Scopus citations

Abstract

In this study, iridotomies were performed in nine rabbit eyes using an Nd:YAG laser at 5.2 mJ, three pulses/burst, for one burst. Prostaglandin E₂ (PGE₂) in aqueous humor obtained at timed intervals after treatment was then measured using a sensitive and specific radioimmunoassay. Concentrations of PGE₂ (mean ± SD pg/ml) were: pretreatment, 377±89; 30 minutes, 1858±241; 120 minutes, 735±308; and 240 minutes, 401±59, postoperatively. The release of PGE₂ into the aqueous humor parallels the rise in intraocular pressure following Nd:YAG iridotomies in rabbits and thus may contribute to this phenomenon.

Original language	English (US)
Pages (from-to)	467-469
Number of pages	3
Journal	Ophthalmic Surgery
Volume	17
Issue number	8
State	Published - 1986

ASJC Scopus subject areas

Ophthalmology

Cite this

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title = "Prostaglandin release following Nd:YAG iridotomy in rabbits",

abstract = "In this study, iridotomies were performed in nine rabbit eyes using an Nd:YAG laser at 5.2 mJ, three pulses/burst, for one burst. Prostaglandin E2 (PGE2) in aqueous humor obtained at timed intervals after treatment was then measured using a sensitive and specific radioimmunoassay. Concentrations of PGE2 (mean ± SD pg/ml) were: pretreatment, 377±89; 30 minutes, 1858±241; 120 minutes, 735±308; and 240 minutes, 401±59, postoperatively. The release of PGE2 into the aqueous humor parallels the rise in intraocular pressure following Nd:YAG iridotomies in rabbits and thus may contribute to this phenomenon.",

author = "R. Gailitis and Peyman, {G. A.} and J. Pulido and Mitchell, {M. D.} and Weinreb, {R. M.}",

year = "1986",

language = "English (US)",

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T1 - Prostaglandin release following Nd:YAG iridotomy in rabbits

AU - Gailitis, R.

AU - Peyman, G. A.

AU - Pulido, J.

AU - Mitchell, M. D.

AU - Weinreb, R. M.

PY - 1986

Y1 - 1986

N2 - In this study, iridotomies were performed in nine rabbit eyes using an Nd:YAG laser at 5.2 mJ, three pulses/burst, for one burst. Prostaglandin E2 (PGE2) in aqueous humor obtained at timed intervals after treatment was then measured using a sensitive and specific radioimmunoassay. Concentrations of PGE2 (mean ± SD pg/ml) were: pretreatment, 377±89; 30 minutes, 1858±241; 120 minutes, 735±308; and 240 minutes, 401±59, postoperatively. The release of PGE2 into the aqueous humor parallels the rise in intraocular pressure following Nd:YAG iridotomies in rabbits and thus may contribute to this phenomenon.

AB - In this study, iridotomies were performed in nine rabbit eyes using an Nd:YAG laser at 5.2 mJ, three pulses/burst, for one burst. Prostaglandin E2 (PGE2) in aqueous humor obtained at timed intervals after treatment was then measured using a sensitive and specific radioimmunoassay. Concentrations of PGE2 (mean ± SD pg/ml) were: pretreatment, 377±89; 30 minutes, 1858±241; 120 minutes, 735±308; and 240 minutes, 401±59, postoperatively. The release of PGE2 into the aqueous humor parallels the rise in intraocular pressure following Nd:YAG iridotomies in rabbits and thus may contribute to this phenomenon.

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Prostaglandin release following Nd:YAG iridotomy in rabbits

Abstract

ASJC Scopus subject areas

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