In this study, iridotomies were performed in nine rabbit eyes using an Nd:YAG laser at 5.2 mJ, three pulses/burst, for one burst. Prostaglandin E2 (PGE2) in aqueous humor obtained at timed intervals after treatment was then measured using a sensitive and specific radioimmunoassay. Concentrations of PGE2 (mean ± SD pg/ml) were: pretreatment, 377±89; 30 minutes, 1858±241; 120 minutes, 735±308; and 240 minutes, 401±59, postoperatively. The release of PGE2 into the aqueous humor parallels the rise in intraocular pressure following Nd:YAG iridotomies in rabbits and thus may contribute to this phenomenon.
|Original language||English (US)|
|Number of pages||3|
|State||Published - 1986|
ASJC Scopus subject areas