TY - JOUR
T1 - Prostaglandin release following Nd:YAG iridotomy in rabbits
AU - Gailitis, R.
AU - Peyman, G. A.
AU - Pulido, J.
AU - Mitchell, M. D.
AU - Weinreb, R. M.
PY - 1986
Y1 - 1986
N2 - In this study, iridotomies were performed in nine rabbit eyes using an Nd:YAG laser at 5.2 mJ, three pulses/burst, for one burst. Prostaglandin E2 (PGE2) in aqueous humor obtained at timed intervals after treatment was then measured using a sensitive and specific radioimmunoassay. Concentrations of PGE2 (mean ± SD pg/ml) were: pretreatment, 377±89; 30 minutes, 1858±241; 120 minutes, 735±308; and 240 minutes, 401±59, postoperatively. The release of PGE2 into the aqueous humor parallels the rise in intraocular pressure following Nd:YAG iridotomies in rabbits and thus may contribute to this phenomenon.
AB - In this study, iridotomies were performed in nine rabbit eyes using an Nd:YAG laser at 5.2 mJ, three pulses/burst, for one burst. Prostaglandin E2 (PGE2) in aqueous humor obtained at timed intervals after treatment was then measured using a sensitive and specific radioimmunoassay. Concentrations of PGE2 (mean ± SD pg/ml) were: pretreatment, 377±89; 30 minutes, 1858±241; 120 minutes, 735±308; and 240 minutes, 401±59, postoperatively. The release of PGE2 into the aqueous humor parallels the rise in intraocular pressure following Nd:YAG iridotomies in rabbits and thus may contribute to this phenomenon.
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M3 - Article
C2 - 3462598
AN - SCOPUS:0022893621
VL - 17
SP - 467
EP - 469
JO - Ophthalmic Surgery and Lasers
JF - Ophthalmic Surgery and Lasers
SN - 2325-8160
IS - 8
ER -