Abstract
Cytologic screening in combination with ablative therapy has helped reduce cervical cancer mortality in the developed world. Despite the success of this approach, cervical cancer remains a major cause of death, especially among women with limited access to health care. Recognition that human papillomaviruses (HPVs) are the main etiologic agent in cervical cancer suggests that a prophylactic vaccine could reduce the incidence of HPV infection and, therefore, achieve cancer control with reduced reliance on costly screening programs. In this review, the rationale for developing a prophylactic HPV vaccine and the potential impact that vaccination would have on cervical cancer screening are discussed.
Original language | English (US) |
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Pages (from-to) | 5-9 |
Number of pages | 5 |
Journal | Diagnostic cytopathology |
Volume | 18 |
Issue number | 1 |
DOIs | |
State | Published - 1998 |
Keywords
- Cervix
- Cytology
- Papillomavirus
- VLP
- Vaccine
ASJC Scopus subject areas
- Pathology and Forensic Medicine
- Histology