Prospective evaluation of Roux-En-Y gastric bypass as primary operation for medically complicated obesity

Bruno M. Balsiger, Frank P. Kennedy, Haitham S. Abu-Lebdeh, Maria Collazo-Clavell, Michael Dennis Jensen, Timothy O'Brien, Donald D. Hensrud, Sean F. Dinneen, Geoffrey B. Thompson, Florencia Que, Donald E. Williams, Matthew M Clark, Jeanne E. Grant, Marsha S. Frick, Roger A. Mueller, Jane L. Mai, Michael G. Sarr

Research output: Contribution to journalArticle

122 Citations (Scopus)

Abstract

Objective: To determine prospectively the results of Roux-en-Y gastric bypass (RYGB) used as the primary weight-reducing operation in patients with medically complicated ('morbid') obesity. The RYGB procedure combines the advantages of a restrictive physiology (pouch of 10 mL) and a 'dumping physiology' for high-energy liquids without requiring an externally reinforced (banded) stoma. Patients and Methods: Between April 1987 and December 1998, a total of 191 consecutive patients with morbid obesity (median weight, 138 kg [range, 91-240 kg]; median body mass index, 49 kg/m2 [range, 36-74 kg/m2), all of whom had directly weight-related morbidity, underwent RYGB and prospective follow-up. Results: Hospital mortality was 0.5% (1/191), and hospital morbidity occurred in 10.5% (20/191). Good longterm weight loss was achieved, and patients adapted well to the required new eating habits. The mean ± SD weight loss at 1 year after operation (113 patients) was 52±1 kg or 68%±2% of initial excess body weight. By 3 years postoperatively (74 patients), weight loss was still 66%±2% of excess body weight. Overall, 53 (72%) of 74 patients had achieved and maintained a weight loss of 50% or more of their preoperative excess body weight 3 years after the operation. In addition, only 1 (1%) of 98 patients had persistent postoperative vomiting 1 or more times per week. Conclusion: We believe that RYGB is a safe, effective procedure for most patients with morbid obesity and thus may be the current procedure of choice in patients requiring bariatric surgery for morbid obesity.

Original languageEnglish (US)
Pages (from-to)673-680
Number of pages8
JournalMayo Clinic Proceedings
Volume75
Issue number7
StatePublished - 2000

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Gastric Bypass
Obesity
Morbid Obesity
Weight Loss
Body Weight
Weights and Measures
Morbidity
Postoperative Nausea and Vomiting
Bariatric Surgery
Feeding Behavior
Hospital Mortality
Body Mass Index

ASJC Scopus subject areas

  • Medicine(all)

Cite this

Balsiger, B. M., Kennedy, F. P., Abu-Lebdeh, H. S., Collazo-Clavell, M., Jensen, M. D., O'Brien, T., ... Sarr, M. G. (2000). Prospective evaluation of Roux-En-Y gastric bypass as primary operation for medically complicated obesity. Mayo Clinic Proceedings, 75(7), 673-680.

Prospective evaluation of Roux-En-Y gastric bypass as primary operation for medically complicated obesity. / Balsiger, Bruno M.; Kennedy, Frank P.; Abu-Lebdeh, Haitham S.; Collazo-Clavell, Maria; Jensen, Michael Dennis; O'Brien, Timothy; Hensrud, Donald D.; Dinneen, Sean F.; Thompson, Geoffrey B.; Que, Florencia; Williams, Donald E.; Clark, Matthew M; Grant, Jeanne E.; Frick, Marsha S.; Mueller, Roger A.; Mai, Jane L.; Sarr, Michael G.

In: Mayo Clinic Proceedings, Vol. 75, No. 7, 2000, p. 673-680.

Research output: Contribution to journalArticle

Balsiger, BM, Kennedy, FP, Abu-Lebdeh, HS, Collazo-Clavell, M, Jensen, MD, O'Brien, T, Hensrud, DD, Dinneen, SF, Thompson, GB, Que, F, Williams, DE, Clark, MM, Grant, JE, Frick, MS, Mueller, RA, Mai, JL & Sarr, MG 2000, 'Prospective evaluation of Roux-En-Y gastric bypass as primary operation for medically complicated obesity', Mayo Clinic Proceedings, vol. 75, no. 7, pp. 673-680.
Balsiger BM, Kennedy FP, Abu-Lebdeh HS, Collazo-Clavell M, Jensen MD, O'Brien T et al. Prospective evaluation of Roux-En-Y gastric bypass as primary operation for medically complicated obesity. Mayo Clinic Proceedings. 2000;75(7):673-680.
Balsiger, Bruno M. ; Kennedy, Frank P. ; Abu-Lebdeh, Haitham S. ; Collazo-Clavell, Maria ; Jensen, Michael Dennis ; O'Brien, Timothy ; Hensrud, Donald D. ; Dinneen, Sean F. ; Thompson, Geoffrey B. ; Que, Florencia ; Williams, Donald E. ; Clark, Matthew M ; Grant, Jeanne E. ; Frick, Marsha S. ; Mueller, Roger A. ; Mai, Jane L. ; Sarr, Michael G. / Prospective evaluation of Roux-En-Y gastric bypass as primary operation for medically complicated obesity. In: Mayo Clinic Proceedings. 2000 ; Vol. 75, No. 7. pp. 673-680.
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abstract = "Objective: To determine prospectively the results of Roux-en-Y gastric bypass (RYGB) used as the primary weight-reducing operation in patients with medically complicated ('morbid') obesity. The RYGB procedure combines the advantages of a restrictive physiology (pouch of 10 mL) and a 'dumping physiology' for high-energy liquids without requiring an externally reinforced (banded) stoma. Patients and Methods: Between April 1987 and December 1998, a total of 191 consecutive patients with morbid obesity (median weight, 138 kg [range, 91-240 kg]; median body mass index, 49 kg/m2 [range, 36-74 kg/m2), all of whom had directly weight-related morbidity, underwent RYGB and prospective follow-up. Results: Hospital mortality was 0.5{\%} (1/191), and hospital morbidity occurred in 10.5{\%} (20/191). Good longterm weight loss was achieved, and patients adapted well to the required new eating habits. The mean ± SD weight loss at 1 year after operation (113 patients) was 52±1 kg or 68{\%}±2{\%} of initial excess body weight. By 3 years postoperatively (74 patients), weight loss was still 66{\%}±2{\%} of excess body weight. Overall, 53 (72{\%}) of 74 patients had achieved and maintained a weight loss of 50{\%} or more of their preoperative excess body weight 3 years after the operation. In addition, only 1 (1{\%}) of 98 patients had persistent postoperative vomiting 1 or more times per week. Conclusion: We believe that RYGB is a safe, effective procedure for most patients with morbid obesity and thus may be the current procedure of choice in patients requiring bariatric surgery for morbid obesity.",
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AU - Kennedy, Frank P.

AU - Abu-Lebdeh, Haitham S.

AU - Collazo-Clavell, Maria

AU - Jensen, Michael Dennis

AU - O'Brien, Timothy

AU - Hensrud, Donald D.

AU - Dinneen, Sean F.

AU - Thompson, Geoffrey B.

AU - Que, Florencia

AU - Williams, Donald E.

AU - Clark, Matthew M

AU - Grant, Jeanne E.

AU - Frick, Marsha S.

AU - Mueller, Roger A.

AU - Mai, Jane L.

AU - Sarr, Michael G.

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N2 - Objective: To determine prospectively the results of Roux-en-Y gastric bypass (RYGB) used as the primary weight-reducing operation in patients with medically complicated ('morbid') obesity. The RYGB procedure combines the advantages of a restrictive physiology (pouch of 10 mL) and a 'dumping physiology' for high-energy liquids without requiring an externally reinforced (banded) stoma. Patients and Methods: Between April 1987 and December 1998, a total of 191 consecutive patients with morbid obesity (median weight, 138 kg [range, 91-240 kg]; median body mass index, 49 kg/m2 [range, 36-74 kg/m2), all of whom had directly weight-related morbidity, underwent RYGB and prospective follow-up. Results: Hospital mortality was 0.5% (1/191), and hospital morbidity occurred in 10.5% (20/191). Good longterm weight loss was achieved, and patients adapted well to the required new eating habits. The mean ± SD weight loss at 1 year after operation (113 patients) was 52±1 kg or 68%±2% of initial excess body weight. By 3 years postoperatively (74 patients), weight loss was still 66%±2% of excess body weight. Overall, 53 (72%) of 74 patients had achieved and maintained a weight loss of 50% or more of their preoperative excess body weight 3 years after the operation. In addition, only 1 (1%) of 98 patients had persistent postoperative vomiting 1 or more times per week. Conclusion: We believe that RYGB is a safe, effective procedure for most patients with morbid obesity and thus may be the current procedure of choice in patients requiring bariatric surgery for morbid obesity.

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