Proposed standard nomenclature for new tumor necrosis factor members involved in the regulation of bone resorption

The American Society For Bone And Mineral Research President'S Committee On Nomenclature

Research output: Contribution to journalArticle

17 Citations (Scopus)

Abstract

Recently, three new family members of the tumor necrosis factor (TNF) ligand and receptor signaling system that play a critical role in the regulation of bone resorption have been identified and cloned. These also have been shown to play an important role in regulating the immune system. A proliferation of synonyms for these molecules has led to miscommunication and redundancy. To resolve this, the President of the American Society for Bone and Mineral Research (ASBMR) appointed a special committee to recommend a standard nomenclature. After considerable deliberation and after vetting by workers in the field, the Committee recommends the names of receptor activator of NF-κB (RANKL) for the membrane receptor, RANK ligand (RANK) for the ligand, and osteoprotegerin (OPG) for the decoy receptor.

Original languageEnglish (US)
Pages (from-to)761-764
Number of pages4
JournalBone
Volume27
Issue number6
DOIs
StatePublished - 2000
Externally publishedYes

Fingerprint

RANK Ligand
Bone Resorption
Terminology
Tumor Necrosis Factor-alpha
Osteoprotegerin
Tumor Necrosis Factor Receptors
Health Personnel
Names
Immune System
Ligands
Membranes

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Histology
  • Physiology

Cite this

The American Society For Bone And Mineral Research President'S Committee On Nomenclature (2000). Proposed standard nomenclature for new tumor necrosis factor members involved in the regulation of bone resorption. Bone, 27(6), 761-764. https://doi.org/10.1016/S8756-3282(00)00420-8

Proposed standard nomenclature for new tumor necrosis factor members involved in the regulation of bone resorption. / The American Society For Bone And Mineral Research President'S Committee On Nomenclature.

In: Bone, Vol. 27, No. 6, 2000, p. 761-764.

Research output: Contribution to journalArticle

The American Society For Bone And Mineral Research President'S Committee On Nomenclature 2000, 'Proposed standard nomenclature for new tumor necrosis factor members involved in the regulation of bone resorption', Bone, vol. 27, no. 6, pp. 761-764. https://doi.org/10.1016/S8756-3282(00)00420-8
The American Society For Bone And Mineral Research President'S Committee On Nomenclature. Proposed standard nomenclature for new tumor necrosis factor members involved in the regulation of bone resorption. Bone. 2000;27(6):761-764. https://doi.org/10.1016/S8756-3282(00)00420-8
The American Society For Bone And Mineral Research President'S Committee On Nomenclature. / Proposed standard nomenclature for new tumor necrosis factor members involved in the regulation of bone resorption. In: Bone. 2000 ; Vol. 27, No. 6. pp. 761-764.
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abstract = "Recently, three new family members of the tumor necrosis factor (TNF) ligand and receptor signaling system that play a critical role in the regulation of bone resorption have been identified and cloned. These also have been shown to play an important role in regulating the immune system. A proliferation of synonyms for these molecules has led to miscommunication and redundancy. To resolve this, the President of the American Society for Bone and Mineral Research (ASBMR) appointed a special committee to recommend a standard nomenclature. After considerable deliberation and after vetting by workers in the field, the Committee recommends the names of receptor activator of NF-κB (RANKL) for the membrane receptor, RANK ligand (RANK) for the ligand, and osteoprotegerin (OPG) for the decoy receptor.",
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AU - John Martin, T.

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AU - Yasuda, Hisataka

AU - Boyce, Brendan F.

AU - Brandi, Maria Luisa

AU - Broadus, Arthur E.

AU - Chambers, Timolthy J.

AU - Delmas, Pierre D.

AU - Dempster, David W.

AU - Felix, Rolf

AU - Fleisch, Herbert A.

AU - Findlay, David M.

AU - Fujita, Toshiro

AU - Kato, Shigeaki

AU - Tanaka, Sakae

AU - Gay, Carol V.

AU - Gilespie, Matthew T.

AU - Hayashi, Shin Ichi

AU - Horton, Michael A.

AU - Kitazawa, Sohei

AU - Kumegawa, Masayoshi

AU - Lorenzo, Joseph

AU - Matsumoto, Toshio

AU - Munday, Gregory R.

AU - David Roodman, G.

AU - Nakamura, Toshitaka

AU - Nicholson, Geoffrey C.

AU - Ogata, Esturo

AU - Ohlsson, Claes

AU - Osdoby, Phillip

AU - Teitelbaum, Steven L.

AU - Oursler, Merry Jo

AU - Wesley Pike, J.

AU - Raisz, Lawrence G.

AU - Rodan, Gideon A.

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AU - Kalervo Vaananen, H.

AU - Zambonin-Zallone, Alberta M.

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