Prolonged shedding of pandemic influenza A (H1N1) 2009 virus in a pancreas-after-kidney transplant recipient

Jackrapong Bruminhent, Paul J. Deziel, Jason T. Wotton, Matthew J. Binnicker, Raymund R. Razonable

Research output: Contribution to journalArticle

5 Scopus citations

Abstract

Prolonged shedding of influenza virus has been reported in immunocompromised patients. Delayed viral clearance may contribute to antiviral resistance and nosocomial transmission. We report a case of a pancreas-after-kidney transplant recipient who had detectable pandemic influenza A virus for 12 months. Pyrosequencing analysis detected the H275Y mutation, which is associated with resistance to oseltamivir.

Original languageEnglish (US)
Pages (from-to)302-304
Number of pages3
JournalJournal of Clinical Virology
Volume61
Issue number2
DOIs
StatePublished - Jan 1 2014

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Keywords

  • Immunocompromised
  • Influenza
  • Oseltamivir
  • Shedding
  • Transmission
  • Transplant

ASJC Scopus subject areas

  • Virology
  • Infectious Diseases

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