Prolonged ambulatory monitoring of colonic motor activity in the pig

M. D. Crowell, F. Musial, W. French, D. Kittur, D. Anderson, W. E. Whitehead

Research output: Contribution to journalArticle

18 Citations (Scopus)

Abstract

The aim of this study was to develop a chronic model suitable for repeated, long-term studies of the interaction of behavior and colonic function in unrestrained pigs. Cecostomies were created in three 20-30 kg micropigs under general anesthesia. Fistulas were created by suturing the bowel to the abdominal wall. Recordings were made by passing a small (8F) solid-state pressure transducer through the fistula into the proximal bowel and connecting it to a battery-operated data logger worn in a vest on the pig's back. Cecostomies have remained patent and trouble-free for over 18 months. No serious infections have occurred. Preliminary data from a total of thirteen 24-h recording sessions showed 54% of all contractile activity to be in the 2-4 cpm frequency range. Increased motility was seen following meals and upon morning awakening. Motility was minimal during the night. Infrequent (10.31 ± 2.05/24 h; mean ± SD) propagated contractions were also noted. These contractions were generally of low amplitude (33.24 ± 3.81 mmHg). These techniques allow prolonged, intraluminal recordings to be made from the colon of the unrestrained pig.

Original languageEnglish (US)
Pages (from-to)471-474
Number of pages4
JournalPhysiology and Behavior
Volume52
Issue number3
DOIs
StatePublished - 1992
Externally publishedYes

Fingerprint

Ambulatory Monitoring
Cecostomy
Motor Activity
Swine
Fistula
Pressure Transducers
Breakfast
Abdominal Wall
General Anesthesia
Colon
Infection

Keywords

  • Ambulatory monitoring
  • Motility
  • Pigs
  • Prolonged recording

ASJC Scopus subject areas

  • Physiology (medical)
  • Behavioral Neuroscience

Cite this

Crowell, M. D., Musial, F., French, W., Kittur, D., Anderson, D., & Whitehead, W. E. (1992). Prolonged ambulatory monitoring of colonic motor activity in the pig. Physiology and Behavior, 52(3), 471-474. https://doi.org/10.1016/0031-9384(92)90332-V

Prolonged ambulatory monitoring of colonic motor activity in the pig. / Crowell, M. D.; Musial, F.; French, W.; Kittur, D.; Anderson, D.; Whitehead, W. E.

In: Physiology and Behavior, Vol. 52, No. 3, 1992, p. 471-474.

Research output: Contribution to journalArticle

Crowell, MD, Musial, F, French, W, Kittur, D, Anderson, D & Whitehead, WE 1992, 'Prolonged ambulatory monitoring of colonic motor activity in the pig', Physiology and Behavior, vol. 52, no. 3, pp. 471-474. https://doi.org/10.1016/0031-9384(92)90332-V
Crowell MD, Musial F, French W, Kittur D, Anderson D, Whitehead WE. Prolonged ambulatory monitoring of colonic motor activity in the pig. Physiology and Behavior. 1992;52(3):471-474. https://doi.org/10.1016/0031-9384(92)90332-V
Crowell, M. D. ; Musial, F. ; French, W. ; Kittur, D. ; Anderson, D. ; Whitehead, W. E. / Prolonged ambulatory monitoring of colonic motor activity in the pig. In: Physiology and Behavior. 1992 ; Vol. 52, No. 3. pp. 471-474.
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