Abstract
The aim of this study was to develop a chronic model suitable for repeated, long-term studies of the interaction of behavior and colonic function in unrestrained pigs. Cecostomies were created in three 20-30 kg micropigs under general anesthesia. Fistulas were created by suturing the bowel to the abdominal wall. Recordings were made by passing a small (8F) solid-state pressure transducer through the fistula into the proximal bowel and connecting it to a battery-operated data logger worn in a vest on the pig's back. Cecostomies have remained patent and trouble-free for over 18 months. No serious infections have occurred. Preliminary data from a total of thirteen 24-h recording sessions showed 54% of all contractile activity to be in the 2-4 cpm frequency range. Increased motility was seen following meals and upon morning awakening. Motility was minimal during the night. Infrequent (10.31 ± 2.05/24 h; mean ± SD) propagated contractions were also noted. These contractions were generally of low amplitude (33.24 ± 3.81 mmHg). These techniques allow prolonged, intraluminal recordings to be made from the colon of the unrestrained pig.
Original language | English (US) |
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Pages (from-to) | 471-474 |
Number of pages | 4 |
Journal | Physiology and Behavior |
Volume | 52 |
Issue number | 3 |
DOIs | |
State | Published - Sep 1992 |
Keywords
- Ambulatory monitoring
- Motility
- Pigs
- Prolonged recording
ASJC Scopus subject areas
- Experimental and Cognitive Psychology
- Behavioral Neuroscience